62452-64-6Relevant articles and documents
Transition-Metal-Free One-Pot Synthesis of Naphthoquinonefuran Derivatives through Sequential Nucleophilic Substitution-Nucleophilic Addition Reaction
Li, Xiang,Sun, Peng,Xie, Kaijun,Zhou, Dun,Peng, Jinsong,Fan, Aihong,Zhang, Jing,Chen, Chunxia
, p. 9313 - 9320 (2020/08/14)
A transition-metal-free route for tandem one-pot synthesis of naphthoquinonefuran derivatives from 2-hydroxynaphthoquinones has been developed. The sequentially accomplished process comprises an intermolecular alkynylation of sp2-carbon at the 3 position of 2-hydroxynaphthoquinones with arylethynyl bromides, followed by a base-promoted intramolecular nucleophilic annulation reaction. A broad range of functional groups is compatible with this reaction, and diverse naphtho[2,3-b]furan-4,9-diones can be obtained with good yields and excellent regioselectivity.
The iodine-mediated highly regioselective synthesis of angular and linear naphthofuroquinones
Liu, Suyou,Long, Lijun,Xie, Duoduo,Liu, Lijun,Ma, Dayou
supporting information, p. 6730 - 6733 (2018/05/14)
Naphthofuroquinones are of great value in medicinal chemistry. In this letter, a facile method for highly regioselective synthesis of both linear and angular naphthofuroquinones has been developed via iodine mediated cyclization of 2-hydroxy-3-substituted