625111-37-7Relevant articles and documents
Synthesis and characterization of oligodeoxyribonucleotides modified with 2′-amino-α-l-LNA adenine monomers: High-affinity targeting of single-stranded DNA
Andersen, Nicolai K.,Anderson, Brooke A.,Wengel, Jesper,Hrdlicka, Patrick J.
, p. 12690 - 12702 (2014/01/17)
The development of conformationally restricted nucleotide building blocks continues to attract considerable interest because of their successful use within antisense, antigene, and other gene-targeting strategies. Locked nucleic acid (LNA) and its diaster
Synthesis of locked nucleic acid derivatives
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Page 15, (2008/06/13)
The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α-L-oxy-LNA, amino-LNA, α-L-amino-LNA, thio-LNA, α-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising