62610-50-8

Basic information

• Product Name: SEPHAROSE CL-6B
• Synonyms: SEPHAROSE CL-6B;SEPHAROSE(R) CL-6B;high resolution agarose;sepharose(R) cl-6B for chromatography;Agarose beads 6% B-CL (Cross-l;Agarose beads 6% B-CL (Cross-linked);sepharose CL-6B-200
• CAS NO: 62610-50-8
• Molecular Formula: NULL
• Molecular Weight: 0
• EINECS: 232-731-8
• Product Categories: Gel Filtration Chromatography;Gel Filtration Media;Gel Filtration MediaResins&LC Separation Media;Protein Chromatography;Sepharose
• Mol File: 62610-50-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 260-481.5℃
• Boiling Point: 100℃
• Flash Point: 39 °C
• Appearance: /
• Density: 1.040
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.679
• Storage Temp.: 2-8°C
• CAS DataBase Reference: SEPHAROSE CL-6B(CAS DataBase Reference)
• NIST Chemistry Reference: SEPHAROSE CL-6B(62610-50-8)
• EPA Substance Registry System: SEPHAROSE CL-6B(62610-50-8)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36-24/25-23
• RIDADR: UN 1170 3/PG 2
• WGK Germany: 1
• HazardClass: 3
• Hazardous Substances Data: 62610-50-8(Hazardous Substances Data)

Usage

Description

SEPHAROSE CL-6B is a versatile and widely used gel matrix derived from cross-linked dextran, which is a polysaccharide composed of glucose units. It is known for its excellent mechanical and chemical stability, as well as its high porosity and large internal surface area. These properties make it an ideal candidate for various applications in the fields of biotechnology, pharmaceuticals, and research.

Uses

Used in Biotechnological Applications:
SEPHAROSE CL-6B is used as a separation medium for protein chromatography, enabling the purification and isolation of proteins based on their size, charge, and hydrophobicity. This is crucial for the development of new drugs, vaccines, and diagnostic tools.
Used in Pharmaceutical Applications:
SEPHAROSE CL-6B is used as a gel filtration chromatography resin, which aids in the purification and separation of biomolecules, such as proteins, peptides, and nucleic acids. This is essential for the production of high-quality pharmaceuticals and the development of novel therapeutic agents.
Used in Research Applications:
SEPHAROSE CL-6B is used as an affinity chromatography matrix, allowing for the specific binding and separation of target molecules, such as enzymes, receptors, and antibodies. This is vital for studying molecular interactions, understanding biological processes, and identifying potential drug targets.
Used in Cancer Research:
SEPHAROSE CL-6B has been employed in the study of in vitro inhibition of human melanoma cells, providing valuable data for anticancer research. Its use in these studies contributes to the development of new cancer therapies and the improvement of existing treatments.
Used in Separation Media:
SEPHAROSE CL-6B serves as an effective separation medium in various industries, including biotechnology, pharmaceuticals, and research. Its high porosity and large internal surface area make it suitable for the separation and purification of a wide range of molecules, from small compounds to large biomolecules.

InChI:InChI=1/C24H38O19/c25-1-5-9(27)11(29)12(30)22(38-5)41-17-8-4-36-20(17)15(33)24(40-8)43-18-10(28)6(2-26)39-23(14(18)32)42-16-7-3-35-19(16)13(31)21(34)37-7/h5-34H,1-4H2/t5-,6-,7+,8+,9+,10+,11+,12-,13+,14-,15+,16-,17-,18+,19+,20+,21-,22+,23+,24+/m1/s1