62663-27-8 Usage
Description
3-(2-phenyl-1H-indol-3-yl)propanoic acid is a chemical compound with a molecular formula C18H17NO2. It belongs to the class of compounds known as indole derivatives, which are widely used in the pharmaceutical and chemical industries. 3-(2-phenyl-1H-indol-3-yl)propanoic acid is a derivative of indole, a heterocyclic aromatic organic compound, and propanoic acid, a carboxylic acid. It has potential applications in medicinal chemistry, particularly for its anti-inflammatory and analgesic properties. Additionally, 3-(2-phenyl-1H-indol-3-yl)propanoic acid may also be used as a building block in the synthesis of other biologically active molecules.
Uses
Used in Pharmaceutical Industry:
3-(2-phenyl-1H-indol-3-yl)propanoic acid is used as an active pharmaceutical ingredient for its anti-inflammatory and analgesic properties. It can be formulated into medications to help alleviate pain and reduce inflammation in various conditions.
Used in Chemical Synthesis:
3-(2-phenyl-1H-indol-3-yl)propanoic acid is used as a building block in the synthesis of other biologically active molecules. Its unique structure allows it to be a valuable component in creating new compounds with potential therapeutic applications.
Used in Medicinal Chemistry Research:
3-(2-phenyl-1H-indol-3-yl)propanoic acid is used as a research tool in medicinal chemistry to study its potential as a lead compound for the development of new drugs. Its properties can be further explored and optimized to create more effective and targeted therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 62663-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,6,6 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 62663-27:
(7*6)+(6*2)+(5*6)+(4*6)+(3*3)+(2*2)+(1*7)=128
128 % 10 = 8
So 62663-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H15NO2/c19-16(20)11-10-14-13-8-4-5-9-15(13)18-17(14)12-6-2-1-3-7-12/h1-9,18H,10-11H2,(H,19,20)
62663-27-8Relevant articles and documents
Synthesis and antimicrobial activity of new series of 2-phenyl-3-[2-(5-substituted-1,3,4-oxadiazol-2-yl) ethyl]-1H-indoles
Purohit, Shriram S.,Kamlesh, Ghori,Kumar, Devendra
, p. 177 - 182 (2019/01/21)
This research article presents the synthesis and antimicrobial activity of a new series of 2-phenyl-3-[2-(5-substituted-1,3,4-oxadiazol-2-yl) ethyl]-1H-indoles 5(a-f). The structures of the compounds were confirmed by FT-IR, 1H NMR and Mass spectral data. All the derivatives have shown moderate to excellent antimicrobial activities. 5a has shown remarkable Minimum Inhibitory Concentration especially against Bacillus subtilis, Klebsiella pneumoniae, Candida albicans, Aspergillus niger when compared with the standard drugs.
Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction
Jennings, Lee D.,Foreman, Kenneth W.,Rush III, Thomas S.,Tsao, Desiree H.H.,Mosyak, Lidia,Kincaid, Scott L.,Sukhdeo, Mohani N.,Sutherland, Alan G.,Ding, Weidong,Kenny, Cynthia Hess,Sabus, Chantel L.,Liu, Hanlan,Dushin, Elizabeth G.,Moghazeh, Soraya L.,Labthavikul, Pornpen,Petersen, Peter J.,Tuckman, Margareta,Ruzin, Alexey V.
, p. 5115 - 5131 (2007/10/03)
The ZipA-FtsZ protein-protein interaction is a potential target for antibacterial therapy. The design and parallel synthesis of a combinatorial library of small molecules, which target the FtsZ binding area on ZipA are described. Compounds were demonstrat