627463-18-7 Usage
General Description
Benzene, 4-bromo-1-ethyl-2-fluoro- (9CI) is a chemical compound that belongs to the halogenated organic compounds class. It is composed of a benzene ring with a bromine atom at the 4th position, an ethyl group at the 1st position, and a fluorine atom at the 2nd position. Benzene, 4-bromo-1-ethyl-2-fluoro- (9CI) is used as a reagent in organic synthesis and pharmaceutical research. It is also known for its potential applications in the production of agrochemicals, pharmaceuticals, and other industries. However, it is important to handle this compound with care due to its potential health hazards, including skin and eye irritation, and its environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 627463-18-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,7,4,6 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 627463-18:
(8*6)+(7*2)+(6*7)+(5*4)+(4*6)+(3*3)+(2*1)+(1*8)=167
167 % 10 = 7
So 627463-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H8BrF/c1-2-6-3-4-7(9)5-8(6)10/h3-5H,2H2,1H3
627463-18-7Relevant articles and documents
DIAMINOTHIAZOLES
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Page/Page column 26, (2010/02/05)
The present invention is directed to novel diaminothiazoles of formula These compounds inhibit cyclin-dependent kinase 4 (Cdk4) and are selective against Cdk2 and Cdk1. These compounds and their pharmaceutically acceptable salts and esters have antiproliferative activity and are useful in the treatment or control of cancer, in particular solid tumors. This invention is also directed to pharmaceutical compositions containing such compounds and to methods of treating or controlling cancer, most particularly the treatment 6r control of breast, lung and colon and prostate tumors.
