62778-16-9

Basic information

• Product Name: (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER
• Synonyms: [(2-methylphenyl)methyl]-phosphonicacidiethylester;DIETHYL (2-METHYLBENZYL)PHOSPHONATE;DIETHYL (O-METHYLBENZYL)PHOSPHONATE;2-(DIETHYLPHOSPHONOMETHYL)TOLUENE;(2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER;Diethyl(2-methylbenzyl)phosphonate, 98 %;[(2-Methylphenyl)methyl]phosphonic acid diethyl ester;(2-Methylbenzyl)-phosphonic acid dimethyl ester
• CAS NO: 62778-16-9
• Molecular Formula: C₁₂H₁₉O₃P
• Molecular Weight: 242.25
• Mol File: 62778-16-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 122°C 0,01mm
• Flash Point: 175.1 °C
• Appearance: /
• Density: 1.09
• Vapor Pressure: 0.000142mmHg at 25°C
• Refractive Index: 1.4980-1.5020
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER(62778-16-9)
• EPA Substance Registry System: (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER(62778-16-9)

Safety Data

• Hazardous Substances Data: 62778-16-9(Hazardous Substances Data)

Usage

General Description

(2-Methylbenzyl)phosphonic acid diethyl ester is a chemical compound that belongs to the class of organophosphorus compounds. It is commonly used as a flame retardant additive in various polymers and plastics due to its ability to reduce the flammability of these materials. It is also employed as a flame retardant in paints, coatings, and adhesives. Additionally, it can be used as a stabilizer and a chelating agent in various industrial processes. (2-METHYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER is characterized by its high thermal stability and effectiveness in preventing the spread of fire, making it a valuable additive in fire safety applications.

InChI:InChI=1/C12H19O3P/c1-4-14-16(13,15-5-2)10-12-9-7-6-8-11(12)3/h6-9H,4-5,10H2,1-3H3

Upstream product

• 552-45-4 1-chloromethyl-2-methylbenzene 
• 122-52-1 triethyl phosphite 
• 529-20-4 2-methylphenyl aldehyde 
• 35629-84-6 N'-(2-methylbenzylidene)-4-methylbenzenesulfonohydrazide 
• 762-04-9 phosphonic acid diethyl ester 
• 78-40-0 triethyl phosphate 
• 89-92-9 2-methylbenzyl bromide 

Downstream Products

• 18869-29-9 (E)-4,4'-dimethylstilbene 
• 2510-76-1 (Z)-4,4'-dimethylstilbene 
• 241155-86-2 C₁₈H₂₀O₂ 
• 241155-87-3 1-Bromo-3-tert-butyl-5-((E)-2-o-tolyl-vinyl)-benzene 
• 1197732-53-8 1,2-dicarboxymethyl-3,6-di-o-tolyl-1,2,4,5-cyclohexadiene 
• 1000672-79-6 (E)-2-(2-methylstyryl)-3,5,6-trimethylpyrazine 
• 13280-61-0 1,4-bis[2-(2-methyl-phenyl)ethenyl]-benzene 
• 137349-01-0 diethyl 2-methyl-4-bromobenzylphosphonate 
• 137349-02-1 diethyl 2-carboxybenzylphosphonate 
• 338732-57-3 2-[3-(2-Methyl-benzyl)-8-aza-bicyclo[3.2.1]oct-8-ylmethyl]-1H-benzimidazole 

Relevant articles and documents

Preparation method of 1,4-bis(2-methylstyryl)benzene

The invention relates to a preparation method of 1,4-bis(2-methylstyryl)benzene. The 1,4-bis(2-methylstyryl)benzene is prepared from diethyl methylbenzylphosphonate and terephthalaldehyde through a reaction. Compared with the prior art, the preparation me

Reductive coupling reactions: A new strategy for C(sp3)-P bond formation

The C(sp3)-P bond forming reaction utilizing N-tosylhydrazones as readily available alkylating reagents was developed, which provides a new opportunity for preparing phosphine oxide derivatives with moderate to good yields. This reductive coupling reaction is proposed to proceed through an insertion of copper carbene into P-H bond of H-phosphorus oxides. The salient features of the reaction are operational simplicity and functional-group tolerance.

Ligustrazine Derivatives. Part 4: Design, Synthesis, and Biological Evaluation of Novel Ligustrazine-based Stilbene Derivatives as Potential Cardiovascular Agents

A series of novel stilbene derivatives containing ligustrazinyl moiety was designed, synthesized, and assayed for their protective effects on damaged endothelial cells. The results showed that most ligustrazinyl stilbene derivatives exhibited high protective effects on the human umbilical vascular endothelial cells (HUVECs) damaged by hydrogen peroxide in comparison with Ligustrazine. The stilbene derivatives A6, A9, A11, A21, A24, A25, and A27 exhibited high potency with low EC50 values ranged from 0.0249μm to 0.0898mm. Compound A27 displayed EC50 0.0249μm, which is 30000 times higher than that of Ligustrazine, presenting a most promising lead for further investigation. Structure-activity relationships were briefly discussed.