628686-08-8

Basic information

• Product Name: 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-pyridin-2-ylethynyl-benzonitrile
• CAS NO: 628686-08-8
• Molecular Weight: 429.481
• Mol File: 628686-08-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-pyridin-2-ylethynyl-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-pyridin-2-ylethynyl-benzonitrile(628686-08-8)
• EPA Substance Registry System: 4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3-pyridin-2-ylethynyl-benzonitrile(628686-08-8)

Safety Data

• Hazardous Substances Data: 628686-08-8(Hazardous Substances Data)

Upstream product

• 182287-63-4 4-bromomethyl-3-iodobenzonitrile 
• 371765-91-2 4-(hydroxy(1-methyl-1H-imidazol-5-yl)methyl)benzonitrile 
• 42872-79-7 3-iodo-4-methylbenzonitrile 
• 1945-84-2 2-ethynylpyridine 
• 450844-38-9 5-[(4-cyano-2-iodobenzyloxy)-(4-cyanophenyl)methyl]-1-methyl-1H-imidazole 

Relevant articles and documents

Synthesis and biological evaluation of 4-[(3-methyl-3H-imidazol-4-yl)-(2-phenylethynyl-benzyloxy)-methyl]-benzonitrile as novel farnesyltransferase inhibitor

Farnesyltransferase inhibitors (FTIs) have emerged as a novel class of anticancer agents. Analogues of the potent FTI, 4-[3-biphenyl-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl] -1-yl-benzonitrile, were synthesized and tested in vitro for their in