629-19-6

Basic information

• Product Name: Propyl disulfide
• Synonyms: N-PROPYL DISULFIDE;PROPYL DISULFIDE;PROPYL DISULPHIDE;PROPYLDITHIOPROPANE;(n-C3H7S)2;1-(Propyldisulfanyl)propane;4,5-Dithiaoctane;Disulfide,dipropyl
• CAS NO: 629-19-6
• Molecular Formula: C₆H₁₄S₂
• Molecular Weight: 150.31
• EINECS: 211-079-8
• Product Categories: Pyridines;pyrazine Flavor
• Mol File: 629-19-6.mol
• Article Data: 108

Chemical Properties

• Melting Point: −86 °C(lit.)
• Boiling Point: 195-196 °C(lit.)
• Flash Point: 151 °F
• Appearance: Clear colorless to pale yellow/Liquid
• Density: 0.96 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.735mmHg at 25°C
• Refractive Index: n20/D 1.497(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: 0.04g/l
• BRN: 969200
• CAS DataBase Reference: Propyl disulfide(CAS DataBase Reference)
• NIST Chemistry Reference: Propyl disulfide(629-19-6)
• EPA Substance Registry System: Propyl disulfide(629-19-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 23-24/25-37/39-26
• RIDADR: 2810
• WGK Germany: 3
• RTECS: JO1955000
• F: 13
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 629-19-6(Hazardous Substances Data)

Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 629-19-6 differently. You can refer to the following data:
1. CLEAR COLURLESS TO PALE YELLOW LIQUID
2. Propyl disulfide has a pungent, sulfur-like odor, with penetrating qualities like the odor of onion and garlic.

Occurrence

Reported found in cabbage, onion, garlic, shallot, roasted onion, raw leek, heated leek, chive, nobiru, caucas, Welsh onion, scallion, grilled and roasted beef and roasted peanut.

Preparation

By boiling propyl bromide and Na2S2 in propyl alcohol; from iodine and n-propyl mercaptan; from propyl iodide and sodium thiosulfate by way of sodium propyl thiosulfate, followed by heating.

Taste threshold values

Taste characteristics at 10 ppm: alliaceous, sulfurous, green, vegetative and asefetida nuances.

General Description

Dipropyl disulfide (DPDS) was an efficient scavenger of reactive oxygen species (ROS) at a lower concentration in both HL-60 and HepG2 cells. It prevents the oxidative DNA damage caused by N-nitrosopiperidine (NPIP) and N-nitrosodibutylamine (NDBA).

InChI:InChI=1/C6H14S2/c1-3-5-7-8-6-4-2/h3-6H2,1-2H3

Upstream product

• 56-23-5 tetrachloromethane 
• 107-03-9 1-thiopropane 
• 141-52-6 sodium ethanolate 
• 10147-36-1 n-propanesulfonyl chloride 
• 594-42-3 chlorothio-trichloro-methane 
• 6898-84-6 sodium 1-propanethiolate 
• 869-56-7 tripropyl phosphorotrithioite 
• 4251-16-5 propyl thiocyanate 
• 540-54-5 1-Chloropropane 
• 6028-61-1 dipropyl trisulfide 
• 5284-66-2 propanesulfonic acid 
• 15780-61-7 S-propyl 3-oxobutanethioate 
• 104-15-4 toluene-4-sulfonic acid 
• 106-94-5 propyl bromide 

Downstream Products

• 1948-52-3 propyl propylthiosulfinate 
• 2280-26-4 S-propylmercapto-L-cysteine 
• 2179-60-4 methyl n-propyl disulfide 
• 17619-36-2 methyl propyl trisulfide 
• 6028-61-1 dipropyl trisulfide 
• 107-03-9 1-thiopropane 
• 3877-15-4 1-(methylthio)-propane 
• 79-05-0 Propionamid 
• 30453-31-7 ethyl propyl disulfide 
• 110-81-6 diethyldisulfane radical cation 
• 20614-39-5 1-propylthio-3-buten-2-ol 
• 98289-57-7 trans-1-propylthio-2-trifluoroacetoxycyclohexane 
• 113261-10-2 2-phenyl-5-propylthiomethyl-4,5-dihydro-1,3-oxazole 
• 116544-93-5 Propane-1-sulfinic acid cyclohexyl ester 

Relevant articles and documents

Nucleophile-induced intramolecular dipole 1,5-transfer and 1,6-cyclization: Experimental and ab initio studies of formation, thermolysis, and molecular and electronic structures of 3,6-diphenyl-1-propanesulfenimido-1,2,4,5-tetrazine

Reaction of dichlorobenzaldazine (2) with sodium azide followed by 1-propanethiol/Et3N furnished tetrazine ylide 1 as the main product. The structure of this unprecedented ylide was confirmed with single-crystal X-ray analysis [C17H17N5S, monoclinic P21/n a = 6.8294(4) A, b = 13.6781(9) A, c = 17.5898(12) A, β = 90.666(1)°, Z = 4] and favorably compared with the results of ab initio calculations. The mechanisms of formation of the ylide and its thermal decomposition to 2,5-diphenyltetrazine (5) were investigated using ab initio methods and correlated with the experimental observations. The results suggest that formation of 1 involves intramolecular cyclization of a nitrile imine and thermolysis of 1 might generate a sulfenylnitrene. The formation of 1 is considered to be the first example of a potentially more general reaction.

Substituted o-Aminophenols as Redox-Mediators in the Thiol Oxidation to Unsymmetrical Disulfides

A number of substituted o-aminophenols has been investigated as redox mediators of the thiol oxidation to disulfides. The electrooxidation of o-aminophenols leads to the corresponding o-iminobenzoquinones. These compounds react with thiols in the solution with a formation of disulfides. It was established that the use of 4,6-di-tert-butyl-2-(tert-butylamino)phenol as a redox mediator can reduce the overpotential of the thiol oxidation by 0.2-1.4 V depending on the nature of the coupling thiols. The unsymmetrical disulfides with alkyl, aryl, and heteroaryl substituents were obtained as the result of the indirect electrosynthesis.

METHOD FOR OXIDATION OF SULFUR-CONTAINING COMPOUNDS

Various embodiments disclosed relate to a method of oxidizing sulfur-containing compounds. The method involves contacting a sulfur-containing compound with a helmet phthalocyaninato-type catalyst in the presence of an oxidant. The present invention also provides a method of removing undesired sulfur-containing compounds from a fluid, such as natural gas, crude oil or an aqueous waste stream.