629-66-3Relevant articles and documents
Rothman,E.S. et al.
, p. 2540 - 2543 (1973)
Sequential removal of photolabile protecting groups for carbonyls with controlled wavelength
Wang, Pengfei,Wang, Yun,Hu, Huayou,Spencer, Cierra,Liang, Xing,Pan, Lurong
, p. 6152 - 6157 (2008/12/22)
(Chemical Equation Presented) A group of robust and easy-to-make photolabile protecting groups (PPGs) for carbonyl compounds has been developed. Sequential removal of different PPGs is achieved via control of irradiation wavelength.
Synthesis of modified Weinreb amides: N-tert-butoxy-N-methylamides as effective acylating agents
Labeeuw, Olivier,Phansavath, Phannarath,Genêt, Jean-Pierre
, p. 7107 - 7110 (2007/10/03)
An efficient preparation of N-methyl-O-tert-butylhydroxylamine hydrochloride has been settled, which allowed the synthesis of modified Weinreb amides. Nucleophilic addition of organolithium and Grignard reagents on these N-tert-butoxy-N-methylamides afforded efficiently the corresponding ketones and reduction with DIBAL furnished the corresponding aldehydes in good yields up to 97%.