6297-20-7 Usage
General Description
2,2-dimethyl-N-phenylhydrazinecarboxamide, also known as semustine, is a chemical compound that belongs to the class of alkylating agents. It is a potent cytotoxic and mutagenic compound that is commonly used in chemotherapy to treat various types of cancers, especially brain tumors. Semustine works by attaching alkyl groups to DNA, causing cross-linking and strand breaks, ultimately leading to cell death. Despite its effectiveness in treating cancer, semustine can cause severe side effects such as bone marrow suppression, gastrointestinal disturbances, and liver toxicity. Due to its hazardous nature, proper precautions must be taken when handling and administering this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 6297-20-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6297-20:
(6*6)+(5*2)+(4*9)+(3*7)+(2*2)+(1*0)=107
107 % 10 = 7
So 6297-20-7 is a valid CAS Registry Number.
6297-20-7Relevant articles and documents
Specificity of the Reaction of 1,1-Dimethylhydrazine with Phenyl Isocyanate
Savel'ev,Khranovskii,Veselov,Grekov,Savel'eva
, p. 96 - 98 (2007/10/03)
According to the data of IR and NMR spectroscopy and ebullioscopy, the reaction of phenyl isocyanate with a large excess of 1,1-dimethylhydrazine gives 1,1 -dimethyl-4-phenylsemicarbazide as the major product. At other reactant ratios, biuret-like structures are formed.
Oxidative cyclization of N'-methylhydrazides with lead tetraacetate (author's transl)
Zinner,Krause
, p. 704 - 714 (2007/10/05)
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