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63158-59-8

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63158-59-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 63158-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,1,5 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63158-59:
(7*6)+(6*3)+(5*1)+(4*5)+(3*8)+(2*5)+(1*9)=128
128 % 10 = 8
So 63158-59-8 is a valid CAS Registry Number.

63158-59-8Relevant articles and documents

SUBSTITUTED INDOLE MCL-1 INHIBITORS

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Paragraph 00406, (2015/12/08)

The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein.

3-(2-Carboxyindol-3-yl)propionic Acid-Based Antagonists of the N-Methyl-D-aspartic Acid Receptor Associated Glycine Binding Site

Salituro, Francesco G.,Harrison, Boyd L.,Baron, Bruce M.,Nyce, Philip L.,Stewart, Kenneth T.,et al.

, p. 1791 - 1799 (2007/10/02)

A series of substituted 3-(2-carboxyindol-3-yl)propionic acids was synthesized and tested as antagonists for the strychnine-insensitive glycine binding site of the NMDA receptor.Chlorine, and other small electron-withdrawing substituents in the 4- and 6-p

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