632628-12-7

Basic information

• Product Name: Pyrido[3,2-d]pyrimidin-2(1H)-one, 7-bromo-1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)thio]-3,4-dihydro- 3-[[[(4-methoxyphenyl)methyl]amino]methyl]-
• CAS NO: 632628-12-7
• Molecular Formula: C28H21BrCl2F2N4O2S
• Molecular Weight: 637.332
• Mol File: 632628-12-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrido[3,2-d]pyrimidin-2(1H)-one, 7-bromo-1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)thio]-3,4-dihydro- 3-[[[(4-methoxyphenyl)methyl]amino]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[3,2-d]pyrimidin-2(1H)-one, 7-bromo-1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)thio]-3,4-dihydro- 3-[[[(4-methoxyphenyl)methyl]amino]methyl]-(632628-12-7)
• EPA Substance Registry System: Pyrido[3,2-d]pyrimidin-2(1H)-one, 7-bromo-1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)thio]-3,4-dihydro- 3-[[[(4-methoxyphenyl)methyl]amino]methyl]-(632628-12-7)

Safety Data

• Hazardous Substances Data: 632628-12-7(Hazardous Substances Data)

Upstream product

• 91872-10-5 2-amino-3,5-dibromo-6-methylpyridine 
• 1996-44-7 2,4-difluorothiophenol 
• 2393-23-9 4-methoxy-benzylamine 
• 1000018-58-5 3,5-dibromo-2-chloro-6-methyl-pyridine 
• 632628-11-6 C₂₇H₁₉Br₂Cl₂F₂N₃O₂S 

Downstream Products

• 547756-25-2 7-bromo-1-(2,6-dichloro-phenyl)-6-(2,4-difluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one 

Relevant articles and documents

P38 MAP kinase inhibitors. part 1: Design and development of a new class of potent and highly selective inhibitors based on 3,4-dihydropyrido[3,2-d]pyrimidone scaffold

A new class of p38 antagonists based on 3,4-dihydropyrido[3,2,-d]pyrimidine scaffold has been developed. These inhibitors exhibit unprecedented selectivity towards p38 over other very closely related kinases. Compounds 25, 33, and 34 were identified as be