63285-19-8

Basic information

• Product Name: acetamide anion
• Synonyms: acetamide anion
• CAS NO: 63285-19-8
• Molecular Weight: 58.0599
• Mol File: 63285-19-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: acetamide anion(CAS DataBase Reference)
• NIST Chemistry Reference: acetamide anion(63285-19-8)
• EPA Substance Registry System: acetamide anion(63285-19-8)

Safety Data

• Hazardous Substances Data: 63285-19-8(Hazardous Substances Data)

Upstream product

• 141-78-6 ethyl acetate 
• 75-05-8 acetonitrile 

Relevant articles and documents

HYDROLYSE BASIQUE ET DECARBOXYLATION D'ESTERS ALLOPHANIQUES EN MILIEU MIXTE ACETONITRILE-EAU: CATALYSE BIFONCTIONNELLE PAR UNE ENTITE FORMEE ENTRE BASE ET SOLVANT

Base catalysed hydrolysis of allophanic esters-models of carboxybiotine- in acetonitrile/water mixture, shows a sharp increase in rate constant in the range of 0.1-0.3 M in water, with a maximum which is interpreted as a balance between two desolvation terms, one concerning the nucleophile, the other the anionic transition state.Moreover, in acetonitrile/water mixtures at low water content (2.10-2 M), a fast hydrolysis (kexpca.0.5 s-1 at 20 deg C) of allophanic esters (carboxy-biotin models) is observed due to catalysis by the enolate of acetamide.This speciesalso catalyses the decarboxylation step, likely behaving as a bifunctional catalyst.