63286-28-2Relevant articles and documents
HERBICIDAL COMPOUNDS
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Page/Page column 101, (2021/04/02)
Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.
tele-Substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3- a]pyrazine-Based Antimalarials
Korsik, Marat,Tse, Edwin G.,Smith, David G.,Lewis, William,Rutledge, Peter J.,Todd, Matthew H.
, p. 13438 - 13452 (2020/12/15)
We have discovered and studied a tele-substitution reaction in a biologically important heterocyclic ring system. Conditions that favor the tele-substitution pathway were identified: the use of increased equivalents of the nucleophile or decreased equivalents of base or the use of softer nucleophiles, less polar solvents, and larger halogens on the electrophile. Using results from X-ray crystallographic and isotope labeling experiments, a mechanism for this unusual transformation is proposed. We focused on this triazolopyrazine as it is the core structure of the in vivo active antiplasmodium compounds of Series 4 of the Open Source Malaria consortium.
An original class of small sized molecules as versatile fluorescent probes for cellular imaging
Sirbu, Doina,Diharce, Julien,Martini?, Ivana,Chopin, Nicolas,Eliseeva, Svetlana V.,Guillaumet, Gérald,Petoud, Stéphane,Bonnet, Pascal,Suzenet, Franck
supporting information, p. 7776 - 7779 (2019/07/08)
An unusual class, compact in size, of fluorescent probes based on pyridazino-1,3a,6a-triazapentalene scaffolds exhibits promising fluorescent properties (quantum yield values up to 73%, large Stokes shifts, emission wavelengths located in the green-yellow