6336-69-2Relevant articles and documents
Synthesis of N-substituted-N-acylthioureas of 4-substituted piperazines endowed with local anaesthetic, antihyperlipidemic, antiproliferative activities and antiarrythmic, analgesic, antiaggregating actions
Ranise, Angelo,Spallarossa, Andrea,Bruno, Olga,Schenone, Silvia,Fossa, Paola,Menozzi, Giulia,Bondavalli, Francesco,Mosti, Luisa,Capuano, Annalisa,Mazzeo, Filomena,Falcone, Giuseppe,Filippelli, Walter
, p. 765 - 780 (2007/10/03)
Three series of N-acyl and N-cyclohexyl- or N-methyl or N-phenyl-thioureas of 4-substituted (methyl, phenyl, 2-pyridyl)piperazines (4-12) were synthesised according to a highly convergent one-pot procedure and tested in vivo (local anaesthetic, anti-hyper