6338-68-7

Basic information

• Product Name: N,N-DIMETHYLETHANESULPHONAMIDE
• Synonyms: N,N-DIMETHYLETHANESULFONAMIDE;N,N-DIMETHYLETHANESULPHONAMIDE;TIMTEC-BB SBB007946;Ethanesulfonamide, N,N-dimethyl-;N,N-Dimethylethansulfonamide;Einecs 228-729-1
• CAS NO: 6338-68-7
• Molecular Formula: C₄H₁₁NO₂S
• Molecular Weight: 137.2
• EINECS: 228-729-1
• Mol File: 6338-68-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 186.7°C at 760 mmHg
• Flash Point: 66.7°C
• Appearance: /
• Density: 1.116g/cm³
• Vapor Pressure: 0.656mmHg at 25°C
• Refractive Index: 1.453
• CAS DataBase Reference: N,N-DIMETHYLETHANESULPHONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIMETHYLETHANESULPHONAMIDE(6338-68-7)
• EPA Substance Registry System: N,N-DIMETHYLETHANESULPHONAMIDE(6338-68-7)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 6338-68-7(Hazardous Substances Data)

Usage

General Description

N,N-Dimethylethanesulphonamide, also known as DMF-SO, is an organic compound with the chemical formula C4H11NO2S. It is a colorless liquid with a mild odor and is soluble in water and most organic solvents. DMF-SO is commonly used as a solvent and reagent in organic synthesis, particularly for the preparation of pharmaceuticals and agrochemicals. It is also used as a plasticizer, corrosion inhibitor, and as a solvent for the processing of polymers. DMF-SO is known for its high boiling point and good thermal stability, making it a versatile and valuable chemical in various industrial applications. However, it should be handled with caution as it is considered harmful if swallowed, inhaled, or in contact with skin, and can cause irritation to the respiratory system and eyes.

InChI:InChI=1/C4H11NO2S/c1-4-8(6,7)5(2)3/h4H2,1-3H3

Upstream product

• 124-40-3 dimethyl amine 
• 594-44-5 Ethanesulfonyl chloride 

Downstream Products

• 128622-75-3 1-<1-Hydroxy-4-t-butyl-cyclohexyl>-ethanesulfonic acid N,N-dimethylamide 
• 128622-76-4 1-<1-Hydroxy-4-t-butyl-cyclohexyl>-ethanesulfonic acid N,N-dimethylamide 
• 1222186-23-3 C₁₄H₃₀N₂O₃S₂ 
• 1222186-22-2 C₁₄H₃₀N₂O₃S₂ 

Relevant articles and documents

Highly enantioselective transfer hydrogenation of racemic α-substituted β-keto sulfonamides: Via dynamic kinetic resolution

Highly enantioselective transfer hydrogenation of β-keto sulfonamides was developed via dynamic kinetic resolution using a chiral Ru(ii) catalyst with an azeotropic solution of HCO2H/Et3N as a hydrogen donor, affording α-substituted β-hydroxyl sulfonamides in good yields with excellent diastereo- and enantioselectivities. This method is featured with mild conditions, easy operation, and a broad substrate scope, which make it possible to find wide applications in the synthesis of natural products and biologically active compounds containing the α-substituted β-hydroxyl sulfonamide core.