634-91-3

Basic information

• Product Name: 3,4,5-TRICHLOROANILINE
• Synonyms: 3,4,5-Trichlorobenzenamine;Aniline, 3,4,5-trichloro-;3,4,5-TRICHLOROANILINE;3,4,5-TRICHLOROANILINE PESTANAL, 250 MG;3,4,5-Trichloroaniline ,98%;3,4,5-Trichloroaniline,97%;3,4,5-Trichloroaniline, 97% 1GR;NSC 115260
• CAS NO: 634-91-3
• Molecular Formula: C₆H₄Cl₃N
• Molecular Weight: 196.46
• EINECS: 211-218-2
• Product Categories: Amines;C2 to C6;Nitrogen Compounds
• Mol File: 634-91-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 97-99 °C(lit.)
• Boiling Point: 321.87°C (rough estimate)
• Flash Point: 144.2 ºC
• Appearance: beige crystalline powder
• Density: 1.540
• Vapor Pressure: 0.000456mmHg at 25°C
• Refractive Index: 1.5596 (estimate)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.85±0.10(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 638880
• CAS DataBase Reference: 3,4,5-TRICHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-TRICHLOROANILINE(634-91-3)
• EPA Substance Registry System: 3,4,5-TRICHLOROANILINE(634-91-3)

Safety Data

• Hazard Codes: T,N
• Statements: 23/24/25-33-50/53
• Safety Statements: 28-36/37-45-60-61
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 634-91-3(Hazardous Substances Data)

Usage

Chemical Properties

BEIGE CRYSTALLINE POWDER

Uses

3,4,5-Trichloroaniline is a useful building block available (see catalogue entries T774090, T774323, and T774025 for its isomers). 3,4,5-Trichloroaniline has been used in the preparation of novel 3,4-dihydroisoquinoline compounds as potential antidepressant agents.

General Description

3,4,5-Trichloroaniline forms tri- and tetrachloroaniline-Pt(II) complexes having good antileukemic activity.

InChI:InChI=1/C6H4Cl3N/c7-4-1-3(10)2-5(8)6(4)9/h1-2H,10H2

Upstream product

• 21928-51-8 5-bromo-1,2,3-trichloro-benzene 
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Downstream Products

• 33715-62-7 N-(3,4,5-trichlorophenyl)acetamide 
• 19010-53-8 N-(3,4-dichloro-phenyl)-N'-(3,4,5-trichloro-phenyl)-urea 
• 76393-46-9 N,N'-bis-(3,4,5-trichloro-phenyl)-urea 
• 35754-32-6 1,2,3-trichloro-5-isothiocyanatobenzene 
• 91821-60-2 N,N'-bis-(3,4,5-trichloro-phenyl)-thiourea 
• 86282-83-9 N-(3,4,5-trichloro-phenyl)-anthranilic acid 
• 117367-27-8 N-(3,4,5-Trichlorphenyl)-2-hydroxybenzamid 
• 634-90-2 1,2,3,5-tetrachlorobenzene 
• 609-19-8 3,4,5-trichlorophenol 
• 599-52-0 2,3,4,4,5,6-hexachlorocyclohexa-2,5-dien-1-one 
• 3107-21-9 3,4,5-trichlorofluorobenzene 
• 87-61-6 1,2,3-trichlorobenzene 
• 88486-08-2 p-Tolyl-(3,4,5-trichloro-phenylamino)-acetonitrile 
• 76842-07-4 2',3,3',4,5-pentachlorobiphenyl 

Relevant articles and documents

General and Chemoselective Copper Oxide Catalysts for Hydrogenation Reactions

Copper oxide catalysts have been prepared by pyrolysis of copper acetate on aluminum oxide. The material resulting from pyrolysis at 800 °C allows for catalytic hydrogenations at low temperature of a variety of unsaturated compounds such as quinolines, alkynes, ketones, imines, and polycyclic aromatic hydrocarbons as well as nitroarenes with good activity and selectivity.

Nitrogen-Doped Graphene-Supported Iron Catalyst for Highly Chemoselective Hydrogenation of Nitroarenes

A nitrogen-doped graphene-supported iron catalyst was used for the first time in the hydrogenation of a series of nitroarenes to give the corresponding amines with excellent activity and chemoselectivity under mild reaction conditions. Physicochemical characterization of the catalyst by transmission electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, and M?ssbauer spectroscopy revealed the formation of iron particles with an iron oxide core and a metallic iron shell that were coated by a few layers of nitrogen-doped graphene. The unique structure of FeNx/C in the catalyst was proven to contribute to the hydrogenation activity.

USE OF THERMALLY-TREATED SUPPORTED COBALT CATALYSTS COMPRISING A POLYCYCLIC AROMATIC STRUCTURE CONSISTING OF NITROGEN LIGANDS FOR HYROGENATING AROMATIC NITRO COMPOUNDS

The invention relates to the use of thermally-treated supported cobalt catalysts for hydrogenating aromatic nitro compounds, the cobalt catalysts having been prepared by in situ immobilization of a cobalt-amine complex on an inorganic porous support and subsequent pyrolysis, and, in the cobalt-amine complex used, cobalt being present bonded to an aromatic or heterocyclic nitrogen ligand L, the nitrogen ligand being selected so as to form a polyaromatic structure with the cobalt atom.