634182-03-9Relevant articles and documents
Ir-catalyzed asymmetric hydrogenation of 3-arylindenones for the synthesis of chiral 3-arylindanones
Yan, Jun,Nie, Yu,Gao, Feng,Yuan, Qianjia,Xie, Fang,Zhang, Wanbin
, (2021/02/27)
An efficient synthesis of chiral 3-arylindanones via iridium-catalyzed asymmetric hydrogenation of 3-arylindenones has been developed. The reaction showed good compatibility with various functional groups, delivering a variety of 3-arylindanones in excellent yields and with good enantioselectivities. The reaction was also carried out on a gram-scale, delivering the product in quantitative yield. In addition, the products can be easily derivatized and transformed into natural products and pharmaceutical agents.
Enantioselective Intramolecular Reductive Heck Reaction with a Palladium/Monodentate Phosphoramidite Catalyst
Mannathan, Subramaniyan,Raoufmoghaddam, Saeed,Reek, Joost N. H.,de Vries, Johannes G.,Minnaard, Adriaan J.
, p. 551 - 554 (2017/02/26)
A palladium-catalyzed enantioselective reductive Heck reaction of enones using monodentate phosphoramidite ligands is described. α,α,α’,α’-tetraaryl-1,3-dioxolane-4,5-dimethanol (TADDOL)-based phosphoramidites with palladium(II) acetate, and N-methyl dicy
Palladium-catalyzed asymmetric reductive Heck reaction of aryl halides
Yue, Guizhou,Lei, Kaining,Hirao, Hajime,Zhou, Jianrong
supporting information, p. 6531 - 6535 (2015/06/08)
Asymmetric reductive Heck reaction of aryl halides is realized in high stereoselectivity. Hydrogen-bond donors, trialkylammonium salts in a glycol solvent, were used to promote halide dissociation from neutral arylpalladium complexes to access cationic, stereoselective pathways.