635697-85-7

Basic information

• Product Name: Alanine, N-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl]-2- methyl-, 1,1-dimethylethyl ester
• CAS NO: 635697-85-7
• Molecular Formula: C25H28Cl2N2O5S
• Molecular Weight: 539.48
• Mol File: 635697-85-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Alanine, N-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl]-2- methyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Alanine, N-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl]-2- methyl-, 1,1-dimethylethyl ester(635697-85-7)
• EPA Substance Registry System: Alanine, N-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]sulfonyl]-2- methyl-, 1,1-dimethylethyl ester(635697-85-7)

Safety Data

• Hazardous Substances Data: 635697-85-7(Hazardous Substances Data)

Usage

Category

Ester

Derived From

Alanine (non-essential amino acid)

Functional Groups

Sulfonyl group
Chloro moiety
Quinolinyl moiety

Application

Pharmaceutical and medicinal research
Potential drug candidate
Intermediate for synthesizing other chemical compounds

Upstream product

• 69145-58-0 2,4-Dichloro-3-methylbenzenesulfonyl chloride 
• 118-69-4 2,6-dichlorotoluene 
• 899797-69-4 2-(2,4-dichloro-3-methylbenzenesulfonylamino)-2-methylpropionic acid tert-butyl ester 
• 899797-70-7 2-(3-bromomethyl-2,4-dichlorobenzenesulfonylamino)-2-methylpropionic acid tert-butyl ester 
• 826-81-3 2-methyl-8-quinolinol 

Relevant articles and documents

Design and synthesis of novel sulfonamide-containing bradykinin hB 2 receptor antagonists. 1. Synthesis and SAR of α,α- dimethylglycine sulfonamides

We recently published the extensive in vivo pharmacological characterization of MEN 16132 (J. Pharmacol. Exp. Ther. 2005, 616-623; Eur. J. Pharmacol. 2005, 528, 7), a member of the sulfonamide-containing human B 2 receptor (hB2R) ant