635698-34-9

Basic information

• Product Name: 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione
• Synonyms: 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione;5H)-dione;6-benzyl-6;6-benzyl-1H,2H,3H,4H,5H,6H,7H-pyrrolo[3,4-d]pyriMidine-2,4-dione;6-Benzyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyriMidine-2,4-diol;1H-Pyrrolo[3,4-d]pyriMidine-2,4(3H,5H)-dione, 6,7-dihydro-6-(phenylMethyl)-;6-Benzyl-1,5,6,7-tetrahydro-pyrrolo[3,4-d]pyrimidine-2,4-dione;6-benzyl-5,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4-dione
• CAS NO: 635698-34-9
• Molecular Formula: C₁₃H₁₃N₃O₂
• Molecular Weight: 243.26
• EINECS: 1533716-785-6
• Product Categories: CHIRAL CHEMICALS;pyrimidine;Heterocycle-Pyrimidine series
• Mol File: 635698-34-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.37g/cm³
• Refractive Index: 1.669
• Storage Temp.: 2-8°C
• PKA: 10.07±0.20(Predicted)
• CAS DataBase Reference: 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione(635698-34-9)
• EPA Substance Registry System: 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione(635698-34-9)

Safety Data

• Hazardous Substances Data: 635698-34-9(Hazardous Substances Data)

Usage

General Description

6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione is a chemical compound with potential applications in pharmaceutical research and drug development. It belongs to the class of pyrrolopyrimidine derivatives and is known for its biological activity as an inhibitor of protein kinases, which are enzymes involved in the regulation of various cellular processes. 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione has been studied for its potential use in the treatment of cancer, autoimmune diseases, and inflammatory disorders. Its unique structural features make it an interesting target for medicinal chemistry and chemical biology studies, where it could lead to the development of novel therapeutic agents with improved efficacy and reduced side effects. Further research is needed to fully understand the pharmacological properties and potential uses of 6-benzyl-6,7-dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione in the field of drug discovery and development.

InChI:InChI=1/C13H13N3O2/c17-12-10-7-16(6-9-4-2-1-3-5-9)8-11(10)14-13(18)15-12/h1-5H,6-8H2,(H2,14,15,17,18)

Upstream product

• 23583-21-3 ethyl-3-benzylamino propionate 
• 1027-35-6 1-Benzyl-4-oxo-pyrrolidine-3-carboxylic Acid Ethyl Ester 
• 57-13-6 urea 

Downstream Products

• 1190927-74-2 2,4-dichloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride 

Relevant articles and documents

BICYCLIC PYRIMIDINE DERIVATIVES

[wherein m and n may be the same or different and each represents an integer of 1 to 3 wherein m + n is 4 or less; R1 represents NR4R5 (wherein R4 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R2 represents the above Formula (II), Formula (IV) or the like; A represents a single bond, -C(=O)-, -SO2-, -OC(=O)- or the like; and R3 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl or the like]ψBicyclic pyrimidine derivatives represented by the above Formula (I), or quaternary ammonium salts thereof, or pharmaceutically acceptable salts thereof, or the like, are provided. These have anti-inflammatory activities or modulation activities on the functions of TARC and/or MDC and are useful for treating and/or preventing a disease which is related to T cells, such as an allergic disease, an autoimmune disease or transplant rejection.