636-20-4 Usage
Description
D-DESTHIOBIOTIN, also known as rac-Desthiobiotin, is a vital intermediate compound in the synthesis of Biotin. It plays a crucial role in the conversion process of Dethiobiotin into Biotin, which has been extensively studied in Escherichia coli using specifically deuterated precursors. This conversion process highlights the importance of D-DESTHIOBIOTIN in the field of biochemistry and its potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
D-DESTHIOBIOTIN is used as an intermediate in the synthesis of Biotin for its essential role in various biological processes. Biotin, also known as Vitamin B7 or Vitamin H, is a water-soluble vitamin that plays a critical role in cell growth, the production of fatty acids, and the metabolism of carbohydrates, fats, and proteins. It is also known to support healthy skin, hair, and nails.
Used in Biochemical Research:
D-DESTHIOBIOTIN is used as a research compound in the study of Biotin synthesis and its conversion from Dethiobiotin in Escherichia coli. This research contributes to the understanding of the metabolic pathways and the role of Biotin in cellular functions, which can lead to the development of new therapeutic strategies and applications in medicine.
Used in Nutritional Supplements:
D-DESTHIOBIOTIN, as a precursor to Biotin, is used in the development of nutritional supplements that aim to address Biotin deficiency and support overall health. These supplements can be particularly beneficial for individuals with certain health conditions or those who require additional Biotin for optimal health.
Check Digit Verification of cas no
The CAS Registry Mumber 636-20-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 636-20:
(5*6)+(4*3)+(3*6)+(2*2)+(1*0)=64
64 % 10 = 4
So 636-20-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m1/s1
636-20-4Relevant articles and documents
Synthesis and Biological Activity of 9-Mercaptodethiobiotin - a Putative Biotin Precursor in Escherichia coli
Baxter, Robert L.,Camp, Dominic J.,Coutts, Andrew,Shaw, Nicholas
, p. 255 - 258 (2007/10/02)
A total synthesis of (+/-)-9-mercaptodethiobiotin 3 via the aldehyde 9 is described.Compound (+/-)-3 does not function as a biotin replacement factor for an E. coli mutant (SA291) lacking the entire biotin synthesis operon (bioABFCD-) but supports growth of an E. coli bioA mutant.Compound (+/-)-3 also supports growth of transformed cells of SA291 carrying a plasmid encoding the E. coli biotin synthase (bioB) gene indicating that the compound may be able to substitute for dethiobiotin 2 as a substrate for biotin synthase.