63870-47-3

Basic information

• Product Name: 3-ethyl-4,5-dihydro-5-(3-methylthiazolidin-2-ylidene)-2-(methylthio)-4-oxothiazolium toluene-p-sulphonate
• Synonyms: 3-ethyl-4,5-dihydro-5-(3-methylthiazolidin-2-ylidene)-2-(methylthio)-4-oxothiazolium toluene-p-sulphonate
• CAS NO: 63870-47-3
• Molecular Formula: C17H22N2O4S4
• Molecular Weight: 446.62758
• EINECS: 264-535-3
• Mol File: 63870-47-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-ethyl-4,5-dihydro-5-(3-methylthiazolidin-2-ylidene)-2-(methylthio)-4-oxothiazolium toluene-p-sulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyl-4,5-dihydro-5-(3-methylthiazolidin-2-ylidene)-2-(methylthio)-4-oxothiazolium toluene-p-sulphonate(63870-47-3)
• EPA Substance Registry System: 3-ethyl-4,5-dihydro-5-(3-methylthiazolidin-2-ylidene)-2-(methylthio)-4-oxothiazolium toluene-p-sulphonate(63870-47-3)

Safety Data

• Hazardous Substances Data: 63870-47-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H15N2OS3.C7H8O3S/c1-4-12-8(13)7(16-10(12)14-3)9-11(2)5-6-15-9;1-6-2-4-7(5-3-6)11(8,9)10/h4-6H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/b9-7-;

Upstream product

• 7648-01-3 3-ethylrhodanin 
• 80-48-8 methyl p-toluene sulfonate 

Relevant articles and documents

Rhodacyanine dyes as antimalarials. 1. Preliminary evaluation of their activity and toxicity

The rhodacyanine dye MKT-077 (1), a potent antitumor agent, was found to possess strong in vitro activity against Plasmodium falciparum and a low cytotoxicity. Several new rhodacyanine dyes related to 1, containing a variety of linked heterocyclic moieties, were synthesized, and their antimalarial potencies were evaluated. The synthetic rhodacyanines were found to have EC50 values against P. falciparum in vitro in the range of 4-300 nM. Several compounds in this series have remarkable selective toxicity profiles (> 100).