642-52-4

Basic information

• Product Name: (-)-Montanine
• Synonyms: (6aS)-5,6a,7,8,9,11-Hexahydro-9β-methoxy-6β,11β-methano-6H-1,3-benzodioxolo[5,6-c][1]benzazepin-8α-ol;2-O-Methylpancracine;Montanine【Haemanthus】
• CAS NO: 642-52-4
• Molecular Formula: C₁₇H₁₉NO₄
• Molecular Weight: 301.33706
• Mol File: 642-52-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (-)-Montanine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-Montanine(642-52-4)
• EPA Substance Registry System: (-)-Montanine(642-52-4)

Safety Data

• Hazardous Substances Data: 642-52-4(Hazardous Substances Data)

Usage

General Description

(-)-Montanine is a naturally occurring chemical compound found in certain plant species such as Amaryllidaceae. It is a tertiary alkaloid with potential medicinal properties, although it is also known to be toxic. Research has shown that (-)-Montanine has anti-tumor and anti-inflammatory effects, making it a subject of interest in the development of new pharmaceuticals. However, its toxicity poses a challenge in its application, and further studies are needed to fully understand its potential medicinal benefits and risks.

Upstream product

• 17680-04-5 (3,4-methylenedioxy)phenylmagnesium bromide 
• 67-56-1 methanol 
• 139025-52-8 (2S*,3R*,4aR*,11S*)-5,11a-cis-11,11a-syn-2,3-epoxy-Δ^1(11a)-8,9-(methylenedioxy)-5,11-methanomorphanthridine 
• 139025-49-3 (+/-)-O-benzylmontanine 
• 139025-49-3 (+/-)-O-benzylcoccinine 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 139025-43-7 Acetic acid (1S,2R,4R,5S)-2-acetoxy-5-(benzo[1,3]dioxole-5-carbonyl)-4-(toluene-4-sulfonylamino)-cyclohexyl ester 
• 144609-78-9 (2S*,3R*,4aR*,11S*,11aR*)-2,3-diacetoxy-11-(acetoxymethyl)-8,9-(methylenedioxy)-5-tosylmorphanthridine 
• 139025-44-8 (1R*,1'S*,2R*,4S*,5R*)-2-<2'-acetoxy-1'-<3'',4''-(methylenedioxy)phenyl>ethyl>-4,5-diacetoxy-1-cyclohexyl-N-tosylamide 
• 139025-45-9 (2S*,3R*,4aR*,11S*,11aR*)-2,3-O-benzylidene-2,3-dihydroxy-11-(hydroxymethyl)-8,9-(methylenedioxy)-5-tosylmorphanthridine 
• 144609-76-7 Acetic acid (1S,2R,4R,5R)-2-acetoxy-5-(1-benzo[1,3]dioxol-5-yl-2-hydroxy-ethyl)-4-(toluene-4-sulfonylamino)-cyclohexyl ester 
• 139883-52-6 (1R*,2R*,4S*,5R*)-4,5-diacetoxy-2-<1'-<3'',4''-(methylenedioxy)phenyl>vinyl>-1-cyclohexyl-N-tosylamide 
• 139039-79-5 C₂₄H₂₇NO₆S 
• 144609-79-0 (2S*,3R*,4aR*,11S*,11aR*)-2,3-dihydroxy-11-(hydroxymethyl)-8,9-(methylenedioxy)-5-tosylmorphanthridine 

Downstream Products

• 21416-14-8 pancracine 
• 606-51-9 (-)-manthine 

Relevant articles and documents

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Total synthesis of montanine-type Amarylliidaceae alkaloids, which possess a 5,11-methanomorphanthridine ring system, through cyclization with sodium bis(2-methoxyethoxy)aluminum hydride: The first stereoselective total syntheses of (±)-montanine, (±)-coc

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