6425-08-7

Basic information

• Product Name: 4,4 -Benzylidendimorpholine
• Synonyms: 4,4 -Benzylidendimorpholine;Brn 0253533;Dimorpholinophenylmethane;Einecs 229-192-6;Morpholine, 4,4'-(phenylmethylene)bis-;Morpholine, 4,4'-benzylidenedi- (7ci,8ci);N,N'-Benzylidenebismorpholine
• CAS NO: 6425-08-7
• Molecular Formula: C₁₅H₂₂N₂O₂
• Molecular Weight: 262.35
• Mol File: 6425-08-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,4 -Benzylidendimorpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4 -Benzylidendimorpholine(6425-08-7)
• EPA Substance Registry System: 4,4 -Benzylidendimorpholine(6425-08-7)

Safety Data

• Hazardous Substances Data: 6425-08-7(Hazardous Substances Data)

Usage

General Description

4,4 -Benzylidendimorpholine is a chemical compound commonly used as a rubber vulcanizing agent and accelerator in the production of rubber products. It functions by promoting the cross-linking of polymer chains in rubber, improving its strength, elasticity, and resistance to wear and tear. This chemical is also known for its ability to improve the aging and thermal resistance of rubber products. Additionally, 4,4 -Benzylidendimorpholine is also used in the production of adhesives, coatings, and other industrial applications due to its ability to enhance the performance and durability of various materials. However, it is important to handle this chemical with care due to its potential skin and respiratory irritant properties.

Upstream product

• 110-91-8 morpholine 
• 100-52-7 benzaldehyde 
• 5660-66-2 2-(trichloromethyl)-1,3-dioxolane 
• 754-05-2 ethenyltrimethylsilane 
• 122699-86-9 1-(Bromo-phenyl-methyl)-pyridinium; bromide 
• 70509-10-3 1-phenyl-3-ethoxy-2-aza-1-butene 
• 1257405-06-3 N-(morpholinobenzyl)-4-nitrobenzamide 
• 122-04-3 4-nitro-benzoyl chloride 
• 100-07-2 4-methoxy-benzoyl chloride 
• 62-23-7 4-nitro-benzoic acid 
• 100-09-4 4-methoxybenzoic acid 
• 619-80-7 4-nitrobenzamide 
• 3424-93-9 4-methoxyphenylacetamide 
• 13368-42-8 4-(trimethylsilyl)morpholine 

Downstream Products

• 6327-69-1 2-morpholin-4-yl-2-phenyl-acetamide 
• 2032-36-2 Thiobenzmorpholid 
• 42079-81-2 6,8-dibromo-2-phenyl-4H-chromen-4-one 
• 1409957-31-8 4-(2,2-difluoro-1-phenyl-2-(phenylsulfonyl)ethyl)morpholine 
• 100-52-7 benzaldehyde 
• 130256-26-7 N-(α-hydroxybenzyl)-4-methylbenzamide 
• 183144-25-4 ethyl (E)-2-diethoxyphosphoryl-3-phenylpropendithioate 
• 3096-95-5 2,6-dimethyl-N-(benzylidene)aniline 
• 114460-92-3 1,3-diphenyl-3-morpholino-1-propyne 
• 129-73-7 bis(4-dimethylaminophenyl)phenylmethane 
• 17330-10-8 2,6-di-tert-butyl-4-(α-phenyl-α-morpholinomethyl)phenol 
• 7334-52-3 benzaldehyde diethyldithioacetal 
• 64545-55-7 bis-(4-ethoxy-phenyl)-phenyl-methane 
• 23837-47-0 α.α-Bis-(4-chlor-benzylmercapto)-toluol 

Relevant articles and documents

Rediscovering aminal chemistry: Copper(ii) catalysed formation under mild conditions

Aminals, the N,N analogues of acetals, have been thoroughly explored in organic chemistry, with a particular focus on heteroaromatic aldehyde lithiation. Nevertheless, the existing methodologies for their formation typically employ harsh conditions limiting their usefulness. In this work, we present an efficient and mild methodology for the preparation of aminals from aromatic aldehydes, including furanic platforms. These mild conditions allowed ease of access to a plethora of aminals and as such we set out to explore previously unaccessible potential applications. By studying the stability of various aminals, we were able to develop a simple aldehyde protecting group based on a commercial diamine which is deprotected under mind conditions. We developed a protocol for the scavenging of genotoxic aldehydes by taking advantage of our methodology and a diamine resin, as well as early studies on the development of a stimuli-responsive release system using a salycil aldehyde derived aminal. This journal is

Copper(I)-catalyzed coupling reaction of aryl boronic acids with N,O-acetals and N,N-aminals under atmosphere leading to α-aryl glycine derivatives and diarylmethylamine derivatives

We demonstrated a copper(I)-catalyzed coupling reaction of aryl boronic acids with N,O-acetals and N,N-aminals leading to the synthesis of α-aryl glycines and diarylmethylamines. Under an ambient atmosphere, this catalytic system could be applied to the activation of a C(sp3)-O bond of N,O-acetals with an ester and an aryl group, or without a coordinating substituent, as well as to a C(sp3)-N bond of N,N-aminals.

Zinc-mediated allylation and alkylation of aminals in the presence of TMSCl and diisopropylamine

(Chemical Equation Presented) An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.