643069-43-6

Basic information

• Product Name: 4-HYDROXY-5-METHOXYQUINOLINE
• Synonyms: 4-HYDROXY-5-METHOXYQUINOLINE;4(1H)-Quinolinone,5-methoxy-(9CI);5-Methoxyquinolin-4-ol;5-methoxyquinolin-4(1H)-one
• CAS NO: 643069-43-6
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Product Categories: METHOXY
• Mol File: 643069-43-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 118-121 °C
• Boiling Point: 351.8 °C at 760 mmHg
• Flash Point: 166.6 °C
• Appearance: /
• Density: 1.258 g/cm³
• Vapor Pressure: 1.97E-05mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 4-HYDROXY-5-METHOXYQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-5-METHOXYQUINOLINE(643069-43-6)
• EPA Substance Registry System: 4-HYDROXY-5-METHOXYQUINOLINE(643069-43-6)

Safety Data

• Hazardous Substances Data: 643069-43-6(Hazardous Substances Data)

Usage

General Description

4-HYDROXY-5-METHOXYQUINOLINE is a chemical compound with the molecular formula C10H9NO2. It is a quinoline derivative with a hydroxyl group and a methoxy group attached to the ring structure. 4-HYDROXY-5-METHOXYQUINOLINE has been studied for its potential pharmaceutical and industrial applications. It has been shown to exhibit antitumor and antimicrobial properties, making it a potentially valuable compound for drug development. Additionally, 4-HYDROXY-5-METHOXYQUINOLINE has been used in the synthesis of coordination compounds, which have applications in materials science and catalysis. Overall, 4-HYDROXY-5-METHOXYQUINOLINE is a versatile compound with various potential uses in the pharmaceutical and industrial fields.

InChI:InChI=1/C10H9NO2/c1-13-9-4-2-3-7-10(9)8(12)5-6-11-7/h2-6H,1H3,(H,11,12)

Upstream product

• 213699-52-6 5-[[(3-methoxyphenyl)amino]methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione 

Downstream Products

• 643069-46-9 4-bromo-5-methoxyquinoline 

Relevant articles and documents

PROCESS FOR PREPARING SUBSTITUTED QUINOLIN-4-OL COMPOUNDS

The invention relates to a process for preparing substituted quinolin-4-ol compounds useful for preparing protein tyrosine kinase (PTK) inhibitors which are useful in treating cancer.

Strategic studies in the syntheses of novel 6,7-substituted quinolones and 7- or 6-substituted 1,6- and 1,7-naphthyridones

This paper describes the different strategies devised and applied to overcome the selectivity issues in the syntheses of 6,7-disubstituted-1H-quinolin-4-one, 7-substituted-1H-1,6-naphthyridin-4-one and 6-substituted-1H-1,7-naphthyridin-4-one derivatives. They allowed us to improve the overall yields and the scaling-up feasibility. Several examples illustrate these strategies with their advantages and drawbacks.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.