64357-39-7

Basic information

• Product Name: Methanone, phenyl(4-propylphenyl)-
• CAS NO: 64357-39-7
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 64357-39-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Methanone, phenyl(4-propylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, phenyl(4-propylphenyl)-(64357-39-7)
• EPA Substance Registry System: Methanone, phenyl(4-propylphenyl)-(64357-39-7)

Safety Data

• Hazardous Substances Data: 64357-39-7(Hazardous Substances Data)

Upstream product

• 51166-13-3 phenyl(4-propylphenyl)methanol 
• 108-94-1 cyclohexanone 
• 455-32-3 benzoyl fluoride 
• 134150-01-9 4-propylphenylboric acid 
• 103-65-1 phenylpropane 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 643001-25-6 [4-(1-bromopropyl)phenyl](phenyl)methanone 
• 124643-60-3 [4-(1H-indol-2-yl)phenyl](phenyl)methanone 
• 854751-08-9 4-propyl-trityl chloride 
• 114795-27-6 1-bromo-1,2-diphenyl-2-(4-propyl-phenyl)-ethene 
• 643001-31-4 1-[4-(benzoyl)phenyl]propan-1-one 
• 96459-47-1 2-Dimethylaminoaethyl-<4-propyl-benzhydryl>-aether 
• 51166-13-3 phenyl(4-propylphenyl)methanol 
• 861578-13-4 1,1-diphenyl-1-(4-propylphenyl) methanol 

Relevant articles and documents

Method for preparing epsilon-caprolactone by using in-situ peroxide

The invention discloses a method for preparing epsilon-caprolactone by using in-situ peroxide. The method efficiently utilizes an in-situ peroxide obtained in a process of oxidizing alcohol by oxygento oxidize cyclohexanone into epsilon-caprolactone, i.e., under the catalysis of a catalyst, an alcohol is oxidized into the corresponding ketone while substances such as peroxy hydroxyl or hydrogen peroxide and the like generated in the process are fully utilized, so that the Baeyer Villiger oxidation reaction from cyclohexanone to epsilon-caprolactone is realized. Compared with a previous epsilon-caprolactone synthesis method, the method of the invention has the advantages that the product yield is remarkably increased, the use efficiency of alcohol is further improved, raw materials and reagents are cheap and easy to obtain, operation is easy, reaction conditions are mild, and the method is clean and environmentally friendly.

A novel synthesis of [4-(3-methyl-1H-indol-2-yl) phenyl] (phenyl)methanone

We have developed a simple route for the synthesis of [4-(3-methyl-1H-indol-2-yl)phenyl](phenyl)methanone from easily available starting materials. The (4-propylphenyl) phenylmethanone was prepared by Friedel Craft's benzoylation of n-propyl benzene with benzoyl chloride in dichloromethane using aluminium chloride as the Lewis acid catalyst. Side chain bromination with N-bromo succinimide in tetra chloro methane furnished the bromo derivative which on oxidation with bis-tetra butyl ammonium dichromate gave 1, 4-diacyl benzene. The target molecule was obtained through Fischer indole cyclisation of the diacyl benzene namely 1-(4-benzoylphenyl)propan-1-one via the formation of the hydrazone, followed by cyclization in presence of boron trifluoride ethyl etherate in acetic acid. The structure of the target molecule was elucidated by IR, H1, C13 NMR, Mass spectroscopy and elemental analysis. This method proves to be an efficient route for the synthesis of [4-(3-methyl-1H-indol-2-yl)phenyl](phenyl)methanone in high yields, thereby facilitating the generation of potential biologically active compounds.

Erbium trifluoromethanesulfonate catalyzed Friedel-Crafts acylation using aromatic carboxylic acids as acylating agents under monomode-microwave irradiation

Erbium trifluoromethanesulfonate is found to be a good catalyst for the Friedel-Crafts acylation of arenes containing electron-donating substituents using aromatic carboxylic acids as the acylating agents under microwave irradiation. An effective, rapid and waste-free method allows the preparation of a wide range of aryl ketones in good yields and in short reaction times with minimum amounts of waste.