64399-26-4

Basic information

• Product Name: 1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile
• Synonyms: 1-(4-chlorophenyl)cyclopentanecarbonitrile;1-(4-chlorophenyl)cyclopentane-1-carbonitrile;Cyclopentanecarbonitrile, 1-(4-chlorophenyl)-;MFCD00019274
• CAS NO: 64399-26-4
• Molecular Formula: C₁₂H₁₂ClN
• Molecular Weight: 205.68338
• EINECS: 264-870-5
• Mol File: 64399-26-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 334.7°C at 760 mmHg
• Flash Point: 139.9°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.000126mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile(64399-26-4)
• EPA Substance Registry System: 1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile(64399-26-4)

Safety Data

• Hazardous Substances Data: 64399-26-4(Hazardous Substances Data)

Usage

General Description

1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile is a chemical compound with the molecular formula C13H11ClN. It is a colorless to pale yellow liquid with a molecular weight of 217.68 g/mol. This chemical is a nitrile derivative and is commonly used in the production of pharmaceuticals and agrochemicals. It is also used as an intermediate in the synthesis of various other organic compounds. 1-(4-Chlorophenyl)-1-cyclopentanecarbonitrile has a variety of industrial applications due to its versatile chemical properties. It is important to handle this chemical with caution as it may be harmful if ingested or comes in contact with the skin or eyes.

InChI:InChI=1/C12H12ClN/c13-11-5-3-10(4-6-11)12(9-14)7-1-2-8-12/h3-6H,1-2,7-8H2

Upstream product

• 4254-02-8 cyclopentanecarbonitrile 
• 106-39-8 bromochlorobenzene 
• 110-52-1 1,4-dibromo-butane 
• 140-53-4 p-chlorobenzyl cyanide 
• 110-56-5 1,4-dichlorobutane 

Downstream Products

• 1616922-78-1 [1-(4-chlorophenyl)cyclopentyl]acetonitrile 
• 1616922-77-0 methanesulfonic acid 1-(4-chlorophenyl)cyclopentylmethyl ester 
• 189810-98-8 1-(4-chlorophenyl)cyclopentane-1-carbaldehyde 
• 143407-77-6 Sodium; (6R,7R)-3-acetoxymethyl-7-{[1-(4-chloro-phenyl)-cyclopentanecarbonyl]-amino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 143407-73-2 Sodium; (6R,7R)-7-{[1-(4-chloro-phenyl)-cyclopentanecarbonyl]-amino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate 
• 143407-69-6 Sodium; (2S,5R,6R)-6-{[1-(4-chloro-phenyl)-cyclopentanecarbonyl]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylate 
• 71501-44-5 1-(4-chlorophenyl)cyclopentane-1-carboxylic acid chloride 
• 162780-92-9 <1-(p-Chlorophenyl)cyclopentyl>carbinyl tosylate 
• 80866-79-1 <1-(p-Chlorophenyl)cyclopentyl>carbinol 
• 80789-69-1 1-(4-chlorophenyl)cyclopentane-1-carboxylic acid 

Relevant articles and documents

Synthesis and Biological Activity of Arylcyclopentane-1-carboxylic Acids Aminoesters

1-Arylcyclopentane-1-carboxylic acids were synthesized by alkaline hydrolysis of the corresponding nitriles. Reactions of the acid chlorides with N,N-dialkylaminoalkyl-and hetarylalkylalkanols provided new aminoester derivatives of 1-arylcyclopentane-1-carboxylic acids. Sympatholytic and adrenolytic activity of the obtained amino esters hydrochlorides was studied.

PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE

The present invention relates to a compound having the general formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.

Solvolysis Reactions: Relative Abilities of Cyclopentyl/Phenyl Groups To Stabilize an Electron-Deficient Carbon

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