64715-88-4Relevant articles and documents
The dinosyl group: A powerful activator for the regioselective alcoholysis of aziridines
Stanetty, Christian,Blaukopf, Markus K.,Lachmann, Bodo,Noe, Christian R.
supporting information; experimental part, p. 3126 - 3130 (2011/07/08)
The N-2,4-dinitrophenylsulfonyl group (dinosyl, DNs) was found to be an excellent choice for the N-activation of aziridines towards ring cleavage with primary, secondary, andsterically demanding tertiary alcohols. Alcoholysis does not need any additional
Synthesis, Regioselective Deprotonation, and Stereoselective Alkylation of Fluoro Ketimines
Welch, John T.,Seper, Karl W.
, p. 2991 - 2999 (2007/10/02)
Fluoroacetone imines of cyclohexylamine, valinol O-methyl ether, and phenylalaninol O-methyl ether and 2-fluorocyclohexanone imines of cyclohexylamine and phenylalaninol O-methyl ether were prepared.The temperature-dependent, regioselective deprotonation of these imines was employed in highly regioselective alkylation reactions.The deprotonation of fluoroacetone cyclohexylimine on the carbon bearing fluorine yielded only a single stereoisomer as determined by low temperature 19F NMR.In contrast, deprotonation of fluoroacetone O-benzyloximes was not regiospecific under any of the conditions examined.
ASYMMETRIC CONJUGATE ADDITION OF COPPER AZAENOLATES AS SYNTHETIC EQUIVALENT OF ENOLATES TO CYCLIC ENONES
Yamamoto, Keiji,Iijima, Masayuki,Ogimura, Yoshinobu
, p. 3711 - 3714 (2007/10/02)
Asymmetric conjugate addition to prochiral cyclic enones was devised by using copper azaenolates derived from an acetone imine of optically active amino ethers which were prepared from α-amino acids, the optical yields of the resulting 3-acetonylcycloalkanones being found to attain as high as 75percent e.e.