649569-56-2 Usage
General Description
Methyl 5-(4-chlorophenyl)thiophene-2-carboxylate is a chemical compound with a molecular formula C13H9ClO2S. It is a thiophene derivative with a methyl ester group and a 4-chlorophenyl substitution at the 5-position. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has potential applications in the field of medicine and agriculture due to its properties and structure. METHYL 5-(4-CHLOROPHENYL)THIOPHENE-2-CARBOXYLATE may undergo various chemical reactions and modifications to produce other important compounds with different properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 649569-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,5,6 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 649569-56:
(8*6)+(7*4)+(6*9)+(5*5)+(4*6)+(3*9)+(2*5)+(1*6)=222
222 % 10 = 2
So 649569-56-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H9ClO2S/c1-15-12(14)11-7-6-10(16-11)8-2-4-9(13)5-3-8/h2-7H,1H3
649569-56-2Relevant articles and documents
Direct Carboxylation of Electron-Rich Heteroarenes Promoted by LiO-tBu with CsF and [18]Crown-6
Shigeno, Masanori,Hanasaka, Kazuya,Sasaki, Keita,Nozawa-Kumada, Kanako,Kondo, Yoshinori
supporting information, p. 3235 - 3239 (2019/02/13)
We herein demonstrate that the combination of LiO-tBu, CsF, and [18]crown-6 efficiently promotes the direct C?H carboxylation of electron-rich heteroarenes (benzothiophene, thiophene, benzofuran, and furan derivatives). A variety of functional groups, including methyl, methoxy, halo, cyano, amide, and keto moieties, are compatible with this system. The reaction proceeds via the formation of a tert-butyl carbonate species.
