64967-39-1 Usage
Description
N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine, also known as N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly, is a white powder chemical compound that serves as a substrate for the continuous spectrophotometric assay of angiotensin-converting enzyme (ACE). It is specifically designed to act as a substrate for ACE, allowing for the measurement of the enzyme's activity and inhibition.
Uses
1. Used in Pharmaceutical Research:
N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine is used as a substrate for the continuous spectrophotometric assay of ACE. This application is crucial in pharmaceutical research for the development of new drugs targeting ACE, which plays a significant role in regulating blood pressure and is a therapeutic target for hypertension and other cardiovascular diseases.
2. Used in Kinetic Spectrophotometric Assay:
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly has been utilized for the kinetic spectrophotometric assay of ACE inhibitory activity. This application is essential in determining the effectiveness of potential ACE inhibitors, which can be used in the treatment of hypertension and other related conditions.
3. Used in Drug Development:
In the drug development industry, N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine is used as a benchmark for evaluating the potency and selectivity of new compounds designed to inhibit ACE. This helps researchers identify promising drug candidates that can potentially be used in the treatment of hypertension and other cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 64967-39-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,9,6 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 64967-39:
(7*6)+(6*4)+(5*9)+(4*6)+(3*7)+(2*3)+(1*9)=171
171 % 10 = 1
So 64967-39-1 is a valid CAS Registry Number.
InChI:InChI=1/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1