6515-09-9

Basic information

• Product Name: 2,3,6-TRICHLOROPYRIDINE
• Synonyms: 2,5,6-Trichloropyridine;2,6-Dichloro-3-chloropyridine;Pyridine,2,3,6-trichloro
• CAS NO: 6515-09-9
• Molecular Formula: C₅H₂Cl₃N
• Molecular Weight: 182.44
• EINECS: 1592732-453-0
• Product Categories: Heterocyclic Compounds
• Mol File: 6515-09-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 66-67 °C
• Boiling Point: 300.44°C (rough estimate)
• Flash Point: 111.159°C
• Appearance: /
• Density: 1.8041 (rough estimate)
• Vapor Pressure: 0.134mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: -3.79±0.10(Predicted)
• CAS DataBase Reference: 2,3,6-TRICHLOROPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,6-TRICHLOROPYRIDINE(6515-09-9)
• EPA Substance Registry System: 2,3,6-TRICHLOROPYRIDINE(6515-09-9)

Safety Data

• Hazardous Substances Data: 6515-09-9(Hazardous Substances Data)

Usage

Safety Profile

A poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofNOx and Clí.

InChI:InChI=1/C5H2Cl3N/c6-3-1-2-9-5(8)4(3)7/h1-2H

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 108-99-6 3-Methylpyridine 
• 2176-62-7 2,3,4,5,6-pentachloropyridine 

Downstream Products

• 253440-88-9 ethyl 3,6-dichloropyridine-2-carboxylate 
• 122509-29-9 triethyl pyridine-2,3,6-tricarboxylate 
• 55304-72-8 2,5,6-trichloro-3-nitropyridine 
• 52208-56-7 3-chloro-2,6-difluoropyridine 
• 500011-91-6 5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester 
• 500008-45-7 rynaxypyr 
• 22841-92-5 (3-chloro-2-pyridyl)hydrazine 
• 13466-35-8 3-chloro-2-hydroxypyridine 
• 1702-17-6 Clopyralid 
• 1702-18-7 3,6-dichloro-2-pyridinecarbonitrile 

Relevant articles and documents

Preparation method of chlorantraniliprole

The invention relates to the field of insecticide synthesis, and discloses a preparation method of chlorantraniliprole. The preparation method comprises the following steps: synthesis of an intermediate I, synthesis of an intermediate II and synthesis of chlorantraniliprole. The method comprises the following steps: reacting 2, 3, 6-trichloropyridine serving as a raw material with hydrazine hydrate under the action of a catalyst A to obtain 3, 6-dichloro-2-hydrazinopyridine, carrying out hydrogenation reduction reaction under the action of a catalyst B to obtain an intermediate I, reacting theintermediate I with diethyl maleate, and preparing the 2-(3-chloropyridine-2-yl)-5-hydroxypyrazole-3-ethyl formate under the action of a catalyst C, and hydrolyzing after bromination to obtain an intermediate II, and preparing chlorantraniliprole from the intermediate II. According to the invention, 2, 3, 6-trichloropyridine is adopted to replace 2, 3-dichloropyridine as a raw material to preparethe intermediate I, so that the defects of difficulty in obtaining the 2, 3-dichloropyridine raw material, harsh synthesis conditions, low yield and the like are avoided, the total reaction yield ofthe intermediate I is improved, the intermediate II is prepared by a one-pot method, the post-treatment operation is reduced, and the synthesis cost of chlorantraniliprole is reduced.

The Specificity of Reductive Dechlorination in the Polychloropyridine Series. Synthesis of 2,3,5-Trichloro- and 2,3,5,6-Tetrachloropyridine

The high specificity of the reduction system zinc and ammonium salts in dimethyl methylphosphonate as solvent is demonstrated in several reductive dechlorination reactions of polychloropyridines.The reduction of pentachloropyridine with zinc/ammonium chloride system in dimethyl methylphosphonate yielded solely 2,3,5,6-tetrachloropyridine.Similarly, the reduction of 2,3,4,5-tetrachloropyridine with zinc and tetramethylammonium salt of methyl methylphosphonate furnished exclusively 2,3,5-trichloropyridine.A synthetic procedure for the preparation of the new ammonium salts of methyl methylphosphonate is given.