65388-04-7

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-
• CAS NO: 65388-04-7
• Molecular Formula: C19H14O7
• Molecular Weight: 354.316
• Mol File: 65388-04-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-(65388-04-7)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-(acetyloxy)-3-[4-(acetyloxy)phenyl]-5-hydroxy-(65388-04-7)

Safety Data

• Hazardous Substances Data: 65388-04-7(Hazardous Substances Data)

Upstream product

• 446-72-0 5,7-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-on 
• 108-24-7 acetic anhydride 
• 491-80-5 5,7-Dihydroxy-3-(4-methoxy-phenyl)-chromen-4-on 

Downstream Products

• 583037-96-1 4-(7-acetoxy-5-hydroxy-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-3-yl)phenyl acetate 
• 104691-86-3 lupiwighteone 
• 65388-05-8 Wighteon-7,4'-diacetat 
• 51225-30-0 erythrinin B 
• 583037-95-0 4-(7-acetyloxy-5-((3-methylbut-2-en-l-yl))-4-oxo-4H-chromen-3-yl)phenyl acetate 

Relevant articles and documents

Induction of enantio-selective apoptosis in human leukemia HL-60 cells by (S)-erypoegin K, an isoflavone isolated from Erythrina poeppigiana

Erypoegin K, an isoflavone isolated from the stem bark of Erythrina poeppigiana, has potent apoptosis-inducing effect on human leukemia HL-60 cells. Erypoegin K has a chiral carbon at the C-2′′ position of its furan ring and naturally occurs as a racemic mixture of (S)- and (R)-isomers. In the present study, we semi-synthesized (RS)-erypoegin K from genistein and separated the optical isomers by HPLC using a chiral column to characterize its apoptosis-inducing activity. Apoptotic cell death was assessed by analyzing caspase-3 and caspase-9 activation, nuclear fragmentation, and genomic DNA ladder formation. (S)-erypoegin K showed exclusive anti-proliferative and apoptosis-inducing activity, with an IC50 value of 90 nM, about 50% lower than that of its racemic mixture (175 nM). By contrast, no apoptosis-inducing activity was shown by the (R)-isomer. In addition, methylglyoxal accumulation in the culture medium was observed only in cells treated with (S)-erypoegin K. These results demonstrated that (S)-erypoegin K is a unique bioactive component that has potent apoptosis-inducing activity on HL-60 cells.

Anti-AGEs and antiparasitic activity of an original prenylated isoflavonoid and flavanones isolated from Derris ferruginea

A new isoflavonoid, 5-hydroxy-3-(4-hydroxyphenyl)-8-isopropenyl-8,9- dihydro-4H-furo-[2,3-h]-chromen-4-one named derrisisoflavone G (1), four known prenylated flavanones (2-5), four known isoflavonoids (6-9) and two phenolic derivatives (10, 11) have been

Selective C-6 prenylation of flavonoids via europium(III)-catalyzed claisen rearrangement and cross-metathesis

Starting from the readily available parent flavonoids, the flavanone 6-prenylnaringenin, the isoflavone 6-prenylgenistein (wighteone, erythrinin B) and a protected derivative of the flavonol 6-prenylquercetin (gancaonin P) have been synthesized in short reaction sequences featuring the title processes as key steps.