6558-64-1 Usage
Description
5-Methyl-imidazo[1,5-a]pyridine, also known as MIP, is a heterocyclic aromatic organic compound with the molecular formula C8H7N3. It is commonly found in cigarette smoke and is recognized as a potent carcinogen, particularly contributing to the development of lung cancer. MIP is formed during the combustion of tobacco and has been identified as a key contributor to the carcinogenic properties of cigarette smoke. Additionally, it is classified as a hazardous air pollutant by the United States Environmental Protection Agency. Research indicates that MIP possesses mutagenic and genotoxic effects on cells, making it a significant health risk associated with tobacco use.
Uses
Used in Environmental and Public Health Research:
5-Methyl-imidazo[1,5-a]pyridine is used as a biomarker in environmental and public health research to study the effects of cigarette smoke exposure. Its presence in cigarette smoke serves as an indicator of the potential carcinogenic risks associated with tobacco use.
Used in Toxicology Studies:
MIP is utilized in toxicology studies to investigate the mutagenic and genotoxic effects of cigarette smoke on cells. Understanding the mechanisms by which MIP induces cellular damage can help in developing strategies to mitigate the harmful effects of tobacco smoke.
Used in Regulatory Compliance and Air Quality Monitoring:
5-Methyl-imidazo[1,5-a]pyridine is used as a reference compound in regulatory compliance and air quality monitoring to assess the presence of hazardous air pollutants. Its identification and quantification in environmental samples can aid in enforcing regulations and ensuring public health safety.
Used in Cancer Research:
MIP is employed in cancer research as a model compound to study the molecular mechanisms underlying the development of lung cancer. Investigating the role of MIP in tumorigenesis can provide insights into the pathogenesis of smoking-related cancers and contribute to the development of targeted therapies.
Used in Chemical Education and Awareness Programs:
5-Methyl-imidazo[1,5-a]pyridine serves as a teaching tool in chemical education and awareness programs to illustrate the harmful effects of cigarette smoke and the importance of tobacco control measures. Educating the public about the presence of potent carcinogens like MIP in cigarette smoke can promote smoking cessation and reduce tobacco-related health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 6558-64-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,5 and 8 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6558-64:
(6*6)+(5*5)+(4*5)+(3*8)+(2*6)+(1*4)=121
121 % 10 = 1
So 6558-64-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2/c1-7-3-2-4-8-5-9-6-10(7)8/h2-6H,1H3
6558-64-1Relevant articles and documents
Preparation method of N- phenyl-2-aminopyrimidine compound and its application
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Paragraph 0213; 0224; 0225; 0226, (2017/04/28)
The invention relates to a new N- phenyl-2-aminopyrimidine compound and a medicine composition containing the compound; the N- phenyl-2-aminopyrimidine compound is applied to treat related disease or symptoms of epidermal growth factor receptor (EGFR), such as treat or improve abnormal cell proliferative disease like cancer.
Substituted imidazo[1,5-A]pyridines
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, (2008/06/13)
Disclosed are e.g. novel 5-(carboxyalkyl)imidazo[1,5-a]pyridines, their derivatives and methods of synthesis. Said compounds are useful as selective thromboxane synthetase inhibitors for the treatment of diseases such as cerebral ischaemia, shock, thrombo
