65671-53-6Relevant articles and documents
ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF
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Page/Page column 224, (2022/02/05)
The subject matter described herein is directed to antibody-CIDE conjugates (Ab-CIDEs) that target BRM for degradation, to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where BRM degradation is beneficial.
Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity
Baba, Reisuke,Hori, Yuichiro,Mizukami, Shin,Kikuchi, Kazuya
supporting information, p. 14310 - 14313 (2012/11/07)
Histone deacetylases (HDACs) are key enzymatic regulators of many cellular processes such as gene expression, cell cycle, and tumorigenesis. These enzymes are attractive targets for drug development. However, very few simple methods for monitoring HDAC ac