65679-14-3

Basic information

• Product Name: P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN
• Synonyms: P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN;P-BROMOPHENACYL-8 REAGENT;P-BROMOPHENACYL-8(TM) REAGENT;4-BROMOPHENACYL THIOCYANATE;2-(4-BROMOPHENYL)-2-OXOETHYL THIOCYANATE;4-BROMOPHENACYL THIOCYANATE, 95+%;thiocyanic acid [2-(4-bromophenyl)-2-keto-ethyl] ester;1-(4-broMophenyl)-2-(cyanosulfanyl)ethan-1-one
• CAS NO: 65679-14-3
• Molecular Formula: C₉H₆BrNOS
• Molecular Weight: 256.13
• EINECS: 604-604-1
• Mol File: 65679-14-3.mol
• Article Data: 29

Chemical Properties

• Melting Point: 148-149
• Boiling Point: 400.8 °C at 760 mmHg
• Flash Point: 196.2 °C
• Appearance: /
• Density: 1.59 g/cm³
• Vapor Pressure: 1.24E-06mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: 2-8°C
• CAS DataBase Reference: P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN(CAS DataBase Reference)
• NIST Chemistry Reference: P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN(65679-14-3)
• EPA Substance Registry System: P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN(65679-14-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 65679-14-3(Hazardous Substances Data)

Usage

General Description

P-Bromophenacyl-8 P-Bromophenacyl Bromide/Crown is a chemical compound that is considered as a specialized derivative produced from the bromination of phenacyl bromide, with a crown ether group. The substance is often used as an intermediate in organic synthesis or utilized for advanced pharmaceutical intermediates. Just like other chemical substances, it must be handled with caution due to its potential reactivity and toxicological properties. Specific detailed information including its physical attributes, reactivity, safety precautions, and disposal methods should be referenced from its Material Safety Data Sheet.

InChI:InChI=1/C9H6BrNOS/c10-8-3-1-7(2-4-8)9(12)5-13-6-11/h1-4H,5H2

Upstream product

• 333-20-0 potassium thioacyanate 
• 99-90-1 para-bromoacetophenone 
• 99-73-0 para-bromophenacyl bromide 
• 532-55-8 Benzoyl isothiocyanate 
• 1147550-11-5 ammonium thiocyanate 
• 28131-17-1 2-(4-bromophenyl)acrylic acid 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 540-72-7 sodium thiocyanide 
• 344790-87-0 1-butyl-3-methylimidazolium thiocyanate 
• 4209-02-3 1-(4-bromophenyl)-2-chloroethan-1-one 
• 19826-89-2 α-methanesulfonyloxy-p-bromoacetophenone 
• 98475-05-9 α-tosyloxy-4-bromoacetophenone 

Downstream Products

• 3884-34-2 4-(4-bromophenyl)-2,3-dihydro-2-oxothiazole 
• 3884-33-1 2-chloro-4-(p-bromophenyl)-thiazole 
• 125488-16-6 4-(4-bromophenyl)-2-(piperidin-1-yl)thiazole 
• 2403-27-2 1-(4-bromophenyl)-3-phenyl-2-propen-1-one 
• 1429934-00-8 dimethyl 5-(cyclohexylimino)-2-(4-bromophenyl)-2-(thiocyanatomethyl)-2,5-dihydrofuran-3,4-dicarboxylate 
• 1429934-02-0 dimethyl 5-(tert-butylimino)-2-(4-bromophenyl)-2-(thiocyanatomethyl)-2,5-dihydrofuran-3,4-dicarboxylate 
• 1429934-01-9 diethyl 5-(tert-butylimino)-2-(4-bromophenyl)-2-(thiocyanatomethyl)-2,5-dihydrofuran-3,4-dicarboxylate 
• 1007583-27-8 2-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}-4,4,4-trifluorobutan-1-ol 
• 1007315-23-2 N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]ethane-1,2-diamine 
• 1007583-39-2 (R)-3-benzyloxy-2-[4-(4-bromo-phenyl)-thiazol-2-ylamino]-propan-1-ol 
• 1007583-04-1 (2S)-2-{[4-(4-bromophenyl)-5-chloro-1,3-thiazol-2-yl]amino}butan-1-ol 
• 1007583-12-1 (1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclobutyl)methanol 
• 1007130-51-9 (2R)-2-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}pentan-1-ol 
• 1007583-10-9 (1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropyl)methanol 

Relevant articles and documents

Visible-Light-Mediated Additive-Free Decarboxylative Ketonization Reaction of Acrylic Acids: An Access to α-Thiocyanate Ketones

Visible-light-mediated additive-free decarboxylative functionalization of acrylic acids has been developed. The reaction uses inexpensive organic dye 9,10-dicyanoanthracene as a photocatalyst and uses the ubiquitous dioxygen as both an oxygen source and an oxidant. Through this mild and environmentally friendly method, a series of important α-thiocyanate ketones can be generated from easily available acrylic acids and ammonium thiocyanate. In addition, the facile transformation of product α-thiocyanate ketones makes this method have great potential for application in organic and pharmaceutical chemistry.

An ionic liquid supported on magnetite nanoparticles as an efficient heterogeneous catalyst for the synthesis of alkyl thiocyanates in water

The present study describes a convenient method to synthesize alkyl thiocyanates from alkyl halides with the use of a novel nanomagnetic-supported organocatalyst (MNP@PEG-ImCl). The new supported ionic liquid is fully characterized by field-emission scanning electron microscopy (FESEM), Fourier-transform infrared (FT-IR), energy dispersive X-ray analysis (EDAX), X-ray powder diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM) as well as thermogravimetric analysis (TGA) techniques. It is noteworthy that we observed easy separation of the catalyst from the reaction mixture by a simple magnetic decantation and its reutilization many times without any appreciable loss of activities.

Visible-Light-Promoted Difunctionalization of Olefins Leading to α-Thiocyanato Ketones

A simple and convenient visible-light-induced difunctionalization of alkenes with ammonium thiocyanate and dioxygen has been developed at room temperature. A series of α-thiocyanato ketones could be easily and efficiently obtained in moderate to good yields through the formation of C-S and C=O bonds simply by using nontoxic and inexpensive Na 2 -Eosin Y as a photocatalyst.