657-27-2 Usage
Synthesis
L-Lysine hydrochloride can be synthesisied by microbial fermentation to give?crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.
Description
A white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble
in alcohol and in ether. It melts at about 260°C with decomposition.
Chemical Properties
White crystalline powder
Uses
Different sources of media describe the Uses of 657-27-2 differently. You can refer to the following data:
1. L-(+)-Lysine Monohydrochloride
2. L-Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine.? L-Lysine Monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
Definition
ChEBI: The hydrochloride salt of L-lysine
Biochem/physiol Actions
L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.
Safety Profile
iWdly toxic by
ingestion. When heated to decomposition it
emits very toxic fumes of HCl and NOx.
Purification Methods
Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]
Check Digit Verification of cas no
The CAS Registry Mumber 657-27-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 657-27:
(5*6)+(4*5)+(3*7)+(2*2)+(1*7)=82
82 % 10 = 2
So 657-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
657-27-2Relevant articles and documents
Chiral Receptors for Lysine Based on Covalently Linked Bis- and Tris-binaphthylphosphoric Acids
Octa-Smolin, Frescilia,Thiele, Maike,Yadav, Rohan,Platzek, André,Clever, Guido H.,Niemeyer, Jochen
supporting information, p. 6153 - 6156 (2018/10/05)
The synthesis and application of three chiral receptors based on the covalent linkage of 1,1′-binaphthylphosphoric acids is reported. The binding of the lysine enantiomers to the chiral receptors was investigated by DOSY-NMR and NMR titrations, revealing that the bisphosphoric acid 1d acts as a highly stereoselective receptor for binding of d-lysine.
Polyunsaturated fatty acid derivatives, pharmaceutical compositions containing the same, method for the preparation thereof, and their use as medicament
-
, (2008/06/13)
The compounds of the Formula (I) STR1 wherein R1 is a C18-24 alkenyl containing at least two double bonds, or --(CH2)n --CH(NH2)m --COOH X is 0, NH or C1-4 alkyl-N, Y is CONH2, COOH or COOMe, wherein Me is hydrogen metal, and R2 is a side chain of a any amino acid except L-GLU or L-ASP at α-position or a group of Formula wherein k is zero or an integer of 1, n is zero or an integer of 1 to 3, m is zero or an integer of 1 to 4, A is hydroxyl or one A is hydroxyl and the other A is hydrogen. M is H or R1 --CO and X and R1 are as defined above and their salts having tyrosine kinase inhibitor activity can be used as antitumor agents.
Sesquiterpene compounds and pharmaceutical compositions containing same, from pachastrella sponges
-
, (2008/06/13)
A new class of novel, biologically active sesquiterpene compounds, pharmaceutical compositions containing them, methods of producing the compounds and compositions and methods of using them are disclosed. This new class of compounds have the generic formulae: STR1 and R1, R2, R3, R4, R5, R6, R7 =H or lower alkyl.
