65806-90-8

Basic information

• Product Name: Z-D-SER(TBU)-OH
• Synonyms: N-ALPHA-BENZYLOXYCARBONYL-O-TERT-BUTYL-D-SERINE;N-ALPHA-CARBOBENZOXY-D-SERINE T-BUTYL ETHER;N-ALPHA-CBZ-O-T-BUTYL-D-SERINE;Z-T-BUTYL-D-SERINE;Z-O-T-BUTYL-D-SERINE;Z-D-SERINE(TBU)-OH;Z-D-SER(TBU)-OH;Z-D-Ser(But)-OH
• CAS NO: 65806-90-8
• Molecular Formula: C₁₅H₂₁NO₅
• Molecular Weight: 295.33
• EINECS: 1533716-785-6
• Product Categories: Z-Amino Acids and Derivatives;Z-Amino acid series
• Mol File: 65806-90-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 465.3 °C at 760 mmHg
• Flash Point: 235.2 °C
• Appearance: White to off-white/Powder
• Density: 1.174 g/cm³
• Storage Temp.: -15°C
• PKA: 3.54±0.10(Predicted)
• CAS DataBase Reference: Z-D-SER(TBU)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-SER(TBU)-OH(65806-90-8)
• EPA Substance Registry System: Z-D-SER(TBU)-OH(65806-90-8)

Safety Data

• Hazardous Substances Data: 65806-90-8(Hazardous Substances Data)

Usage

General Description

"Z-D-SER(TBU)-OH" is a chemical compound that consists of Z-D-serine and tert-butyl ester groups. Z-D-serine is a derivative of the amino acid serine, while the tert-butyl ester group is a common protecting group used in organic synthesis to prevent unwanted reactions. Z-D-SER(TBU)-OH can be used as a precursor in the synthesis of various peptides or as a building block for the development of new pharmaceuticals. The compound is also utilized in research laboratories for the study of biochemical pathways and protein interactions. Overall, "Z-D-SER(TBU)-OH" has applications in both academic and industrial settings as a versatile and valuable chemical reagent.

Upstream product

• 93204-37-6 (2R)-2-(benzyloxycarbonylamino)-3-tert-butoxypropionic acid methyl ester 
• 1872-59-9 (S)-methyl 2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoate 

Downstream Products

• 713122-06-6 (Z)-D-Ser{(Z)-D-Ser[Boc-L-Ala-L-Cys(Acm)-L-Val]-L-Ala-L-Cys(Acm)-L-Val}-OH 
• 82662-00-8 N-benzyloxycarbonyl-O-(N-t-butyloxycarbonyl-L-alanyl-S-acetamidomethyl-L-cysteinyl-L-valyl)-D-serine 
• 63520-00-3 (N-benzyloxycarbonyl-D-seryl-L-alanyl-L-cysteinyl-L-valine)2(serine hydroxyl)dilactone disulfide 
• 713122-02-2 (Z)-D-Ser[N-Boc-Cys(Acm)-L-Val]-OTce 
• 713122-04-4 (Z)-D-Ser[L-Ala-L-Cys(Acm)-L-Val]-OTce 
• 713122-03-3 (Z)-D-Ser[N-Boc-L-Ala-L-Cys(Acm)-L-Val]-OTce 
• 713122-20-4 [(1R,4S,7R,11S,14R,17S,20R,24S)-20-(9H-Fluoren-9-ylmethoxycarbonylamino)-11,24-diisopropyl-4,17-dimethyl-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexaaza-bicyclo[12.12.4]triacont-7-yl]-carbamic acid benzyl ester 
• 713122-19-1 C₅₆H₇₂N₈O₁₇S₂ 
• 713122-18-0 (Z)-D-Ser{Fmoc-D-Ser[Boc-L-Ala-L-Cys(Acm)-L-Val]-L-Ala-L-Cys(Acm)-L-Val}-OH 
• 713122-17-9 (Z)-D-Ser{Fmoc-D-Ser[Boc-L-Ala-L-Cys(Acm)-L-Val]-L-Ala-L-Cys(Acm)-L-Val}-OTce 
• 1282623-41-9 O-tert-butyl-N-Z-D-serine benzylamide 
• 1282623-42-0 O-tert-butyl-D-serine benzylamide 
• 1084734-33-7 (R)-2-acetamido-N-benzyl-3-tert-butoxypropionamide 
• 1333115-00-6 (S)-2-((2-amino-3-(tert-butoxy)propoxy)methyl)benzoic acid 

Relevant articles and documents

Synthesis of 6, desGly10>GnRH-Et without Side-Chain Protection

A gonadoliberin superagonist, 6, desGly1>GnRH-Et* (5), was obtained in solution by connecting segments, Glp-His-Trp-Ser-Tyr-N2H3 (1) and Z-DSer(tBu)-LeuArg(AcOH)-Pro-NHEt (4) (Scheme 1), which were produced witho