65837-49-2

Basic information

• Product Name: 2-Azetidinone, 4-(hydroxymethyl)-1-phenyl-
• CAS NO: 65837-49-2
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 65837-49-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Azetidinone, 4-(hydroxymethyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone, 4-(hydroxymethyl)-1-phenyl-(65837-49-2)
• EPA Substance Registry System: 2-Azetidinone, 4-(hydroxymethyl)-1-phenyl-(65837-49-2)

Safety Data

• Hazardous Substances Data: 65837-49-2(Hazardous Substances Data)

Upstream product

• 77692-61-6 1-Phenyl-4-oxo-azetidin-2-carbonsaeure 
• 76228-12-1 4-Oxo-1-phenyl-azetidin-2-carbonsaeure-ethylester 
• 5634-63-9 diethyl 4-oxo-1-phenylazetidine-2,2-dicarboxylate 
• 16940-66-2 sodium tetrahydroborate 

Downstream Products

• 86694-82-8 4-(methylsulfonyloxymethyl)-1-phenylazetidin-2-one 
• 103841-47-0 N-(4-oxo-1-phenylazetidin-2-ylmethyl)pyridinium iodide 
• 103841-46-9 (4-oxo-1-phenylazetidin-2-ylmethyl)ammonium chloride 
• 111781-81-8 1-(p-nitrophenyl)-4-tosyloxymethyl-2-azetidinone 
• 111781-80-7 1-(o-nitrophenyl)-4-tosyloxymethyl-2-azetidinone 
• 103841-44-7 C₂₈H₂₅N₂OP 
• 111781-92-1 1-(p-aminophenyl)-4-tosyloxymethyl-2-azetidinone 
• 103841-43-6 4-azidomethyl-1-phenylazetidin-2-one 
• 103841-45-8 4-({[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-amino}-methyl)-1-phenyl-azetidin-2-one 
• 103841-42-5 4-benzylthiomethyl-1-phenylazetidin-2-one 
• 103841-38-9 4-oxo-1-phenylazetidin-2-ylmethyl nitrate 
• 111781-91-0 2,2a,3,4-tetrahydro-1H-azeto<1,2-a>quinoxalin-1-one 
• 94271-42-8 4-cyanomethyl-1-phenylazetidin-2-one 
• 86694-83-9 4-iodomethyl-1-phenylazetidin-2-one 

Relevant articles and documents

Rearrangement of 1-phenyl-β-lactams by aluminium chloride catalysis

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Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group

The invention relates to new heterocyclic compound containing an alkoxycarbonyl and a substituted methyl group a process for the preparation of these and analogeous compound and pharmaceutical compositions containing them. More particularly, the invention concerns compounds of the general formula (IVa) STR1 wherein R' is hydrogen, 2-ethoxycarbonylethyl, aryl or a group suitable for a temporary protection of amides and Y' represents a group of the formula --COOZ or --CH2 M, in which Z is lower alkyl and M is hydroxyl, halogen, cyano or a group of the formula --O--SO2 R2, in which R2 is lower alkyl or aryl, with the proviso that if R' is phenyl, Y' cannot stand for the group --COOC2 H5. The invention further relates to a process for the preparation of compounds of the general formula (IV) STR2 in which R and Y are identical with R' and Y', respectively, except the proviso. According to a further aspect of the invention there are provided pharmaceutical compositions, first of all with antihypoxic activity, comprising compounds of the general formula (IVa) as active ingredient.