65885-67-8

Basic information

• Product Name: diphenylmethyl 22β-hydroxy-3-oxoolean-12-en-28-onate
• Synonyms: diphenylmethyl 22β-hydroxy-3-oxoolean-12-en-28-onate
• CAS NO: 65885-67-8
• Molecular Weight: 636.915
• Mol File: 65885-67-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diphenylmethyl 22β-hydroxy-3-oxoolean-12-en-28-onate(CAS DataBase Reference)
• NIST Chemistry Reference: diphenylmethyl 22β-hydroxy-3-oxoolean-12-en-28-onate(65885-67-8)
• EPA Substance Registry System: diphenylmethyl 22β-hydroxy-3-oxoolean-12-en-28-onate(65885-67-8)

Safety Data

• Hazardous Substances Data: 65885-67-8(Hazardous Substances Data)

Upstream product

• 10545-79-6 22β-hydroxy-3-oxo-olean-12-en-28-oic acid 
• 908093-98-1 diazodiphenylmethane 

Downstream Products

• 10080-49-6 lantadene B 
• 88034-27-9 lantadene C 

Relevant articles and documents

Lantadenes and their esters as potential antitumor agents

Lantadenes are pentacyclic triterpenoids of the weed Lantana camara. Five new lantadenes (14-18) and their methyl esters (20-24) were synthesized, characterized, and screened for cytotoxicity against four human cancer cell lines. The parent compound (1) and the four most active compounds (15, 16, 21, and 22) were further studied for their in vivo tumor inhibitory potential on squamous cell carcinogenesis in Swiss albino mice induced by 7,12-dimethylbenz[a]anthracene (DMBA) and promoted by 12-O-tetradecanoylphorbol- 13-acetate (TPA). These results were supported by histopathological studies and discussed in terms of structure-activity relationships. The results inferred the importance of the groups attached to C-22 and C-17 in relation to the antitumor activity of these compounds.