66127-06-8Relevant articles and documents
Halotrifluoromethylation of 1,3-Enynes: Access to Tetrasubstituted Allenes
Huang, Jinfeng,Jia, Yimin,Li, Xiangyu,Duan, Jianli,Jiang, Zhong-Xing,Yang, Zhigang
supporting information, p. 2314 - 2319 (2021/04/05)
A highly regioselective copper-catalyzed 1,4-chloro- and bromotrifluoromethylation of 1,3-enynes has been presented for the first time, which affords an efficient transformation to access halo- and CF3-containing tetrasubstituted allene derivatives with good to excellent yield. This protocol is practical and convenient, in which a wide range of functional groups are compatible. Applications of this method for the gram-scale preparation and late-stage functionalization of biologically active molecules are also demonstrated.
Syntheses of new compounds with local anesthetic activity, IX: syntheses of new phenyl benzyl ethers
Oelschlaeger,Czasch,Iglesias-Meier,et al.
, p. 81 - 97 (2007/10/05)
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