661489-23-2 Usage
Description
(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is an organic compound characterized by its unique molecular structure, which features an acrylonitrile group attached to an amino-substituted phenyl ring with dimethyl groups at the 3 and 5 positions. (E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is of interest in the field of medicinal chemistry due to its potential applications in the development of therapeutic agents.
Uses
Used in Pharmaceutical Industry:
(E)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile Hydrochloride is used as a key intermediate in the synthesis of 5,6-substituted pyrimidines, which are important for the development of new antiviral drugs. Specifically, these pyrimidines have the potential to inhibit HIV strains that are resistant to reverse transcriptase inhibitors, offering a promising avenue for the treatment of drug-resistant HIV infections.
Check Digit Verification of cas no
The CAS Registry Mumber 661489-23-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,1,4,8 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 661489-23:
(8*6)+(7*6)+(6*1)+(5*4)+(4*8)+(3*9)+(2*2)+(1*3)=182
182 % 10 = 2
So 661489-23-2 is a valid CAS Registry Number.
InChI:InChI=1S/C11H12N2.ClH/c1-8-6-10(4-3-5-12)7-9(2)11(8)13;/h3-4,6-7H,13H2,1-2H3;1H/b4-3+;
661489-23-2Relevant articles and documents
Rilpivirine midbody preparing technology
-
Paragraph 0017; 0018; 0019; 0020, (2016/11/28)
The invention belongs to the field of medicinal chemistry, and particularly relates to a rilpivirine midbody preparing technology. The technology comprises the steps that 1, 4-bromo-2,6-dimethylaniline and acrylonitrile react under the catalysis of pallad
RILPIVIRINE HYDROCHLORIDE
-
Paragraph 0089; 0090, (2014/12/09)
The present invention provides a novel process for the preparation of rilpivirine. The present invention also provides a novel process for the preparation of rilpivirine hydrochloride. The present invention further provides a rilpivirine hydrochloride monohydrate, process for its preparation and pharmaceutical compositions comprising it.
RILPIVIRINE PROCESS
-
, (2014/09/30)
Disclosed is process for the preparation of a key Rilpivirine intermediate namely, (E)-4-(2-cyanoethenyl)-2,6-dimethylphenylamine hydrochloride (II) by a process comprising reaction of the tetrafluoroborate salt of the diazonium ion of 2,6-dimethyl-4-amin
