66295-44-1

Basic information

• Product Name: diisopropyl methylphosphonite
• Synonyms: diisopropyl methylphosphonite;Methylphosphonous acid bis(1-methylethyl) ester
• CAS NO: 66295-44-1
• Molecular Formula: C₇H₁₇O₂P
• Molecular Weight: 164.182441
• EINECS: 266-302-1
• Mol File: 66295-44-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 161.7°Cat760mmHg
• Flash Point: 55.6°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 2.93mmHg at 25°C
• CAS DataBase Reference: diisopropyl methylphosphonite(CAS DataBase Reference)
• NIST Chemistry Reference: diisopropyl methylphosphonite(66295-44-1)
• EPA Substance Registry System: diisopropyl methylphosphonite(66295-44-1)

Safety Data

• Hazardous Substances Data: 66295-44-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H17O2P/c1-6(2)8-10(5)9-7(3)4/h6-7H,1-5H3

Upstream product

• 676-83-5 methyldichlorophosphane 
• 67-63-0 isopropyl alcohol 
• 71196-16-2 2-methyl-2,3-dihydro-benzo[1,3,2]oxazaphosphole 

Downstream Products

• 6225-86-1 Allylmethylphosphinic acid isopropylester 
• 99687-69-1 Co(P(CH₂CH₂P(C₆H₅)2)3)(P(CH₃)(OCH(CH₃)2)2)⁽¹⁺⁾*AsF₆^(1-) = {Co(P(CH₂CH₂P(C₆H₅)2)3)(P(CH₃)(OCH(CH₃)2)2)}AsF₆ 
• 51807-11-5 ethane-P,P'-dimethyl-1,2-diphosphinic acid 
• 1445-76-7 methylphosphonic chloride isopropyl ester 

Relevant articles and documents

Preparation method of dialkyl methylphosphonite

The invention relates to a preparation method of dialkyl methylphosphonite. tertiary amine with pKa greater than 10 is adopted as the acid binding agent, methyl phosphonic dichloride and alcohol react in a solvent, and the mole ratio of the methyl phosphonic dichloride, alcohol and tertiary amine is 1:2.0-2.4:2.0-2.4, the produced tertiary amine hydrochloride is neutralized with a caustic soda aqueous solution, and the solvent and tertiary amine obtained by evaporation is recycled and reused. The alkyl of the dialkyl methylphosphonite is straight chain and side chain alkane or alkene of aliphatic C1-C4, the alcohol refers to methanol, ethanol, propanol, isopropanol, allyl alcohol, n-butanol, isobutanol and the like, the tertiary amine refers to tertiary fatty amine, and also refers to fatty group and aromatic mixed tertiary amine, at the same time, the pKa of the tertiary amine is required to be greater than 10, and the tertiary amine can include triethylamine, tripropylamine and tributylamine.

Polyoxides de polyphosphines macrocycliques P-alkyles

With the aim of obtaining complexes of γ-emitters and paramagnetic ions for use as imaging reagents and contrast agents, the synthesis of ligands was performed by cyclocondensation between dioxophosphids, α,ω-dihalogenoalkanes, and alkenes.These reactions lead to new cyclic P-alkylated polyphosphine polyoxides with saturated and unsaturated bridges.The 1:1 cyclocondensation products are obtained predominantly over the 2:2 and 3:3 cyclocondensation products.The formation of tetraphosphorated cycles becomes significant when it is allowed by the dihalide configuration.The origin of these orientations is discussed and a mechanism is als o presented for these reactions.Key words: cyclocondensation; cyclic polyphosphine polyoxide; dioxodiphosphid; α,ω-dihalide; P-alkylated phosphorus macrocycle