664969-54-4

Basic information

• Product Name: LF3
• Synonyms: LF3;4-[(2E)-3-phenylprop-2-en-1-yl]-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide
• CAS NO: 664969-54-4
• Molecular Formula: C20H24N4O2S2
• Molecular Weight: 416.56016
• EINECS: -0
• Mol File: 664969-54-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 609.6±65.0 °C(Predicted)
• Appearance: /
• Density: 1.341±0.06 g/cm3(Predicted)
• PKA: 10.00±0.12(Predicted)
• CAS DataBase Reference: LF3(CAS DataBase Reference)
• NIST Chemistry Reference: LF3(664969-54-4)
• EPA Substance Registry System: LF3(664969-54-4)

Safety Data

• Hazardous Substances Data: 664969-54-4(Hazardous Substances Data)

Usage

Description

LF3, also known as N-[4-(Aminosulfonyl)phenyl]-4-(3-phenyl-2-propenyl)-1-piperazinecarbothioamide, is a 4-thioureido-benzenesulfonamide derivative that functions as a Wnt/β-catenin signaling inhibitor. This signaling pathway plays a crucial role in embryogenesis and tissue homeostasis, making LF3 a potentially valuable compound in various applications.

Uses

Used in Pharmaceutical Industry:
LF3 is used as a Wnt/β-catenin signaling inhibitor for its potential role in regulating embryogenesis and tissue homeostasis. By targeting this pathway, LF3 may have therapeutic applications in treating conditions related to abnormal Wnt/β-catenin signaling.
Used in Cancer Research:
LF3 is used as a research tool for studying the role of Wnt/β-catenin signaling in cancer development and progression. Understanding the mechanisms by which LF3 inhibits this pathway can provide insights into the development of novel cancer therapies.
Used in Drug Development:
LF3 is used as a lead compound in the development of new drugs targeting the Wnt/β-catenin signaling pathway. Its unique structure and inhibitory properties make it a promising candidate for further optimization and development into a therapeutic agent.
Used in Tissue Engineering and Regenerative Medicine:
LF3 is used as a modulator of tissue homeostasis for its potential to influence the Wnt/β-catenin signaling pathway, which is involved in tissue repair and regeneration. This application may lead to advancements in tissue engineering and regenerative medicine strategies.