6681-15-8

Basic information

• Product Name: JATRORRHIZINE HCL(RG)
• Synonyms: JATRORRHIZINE HCL(RG);Jatrorrhizine，Neprotine chloride，Yatrorhizine chloride;Jatorrhizine, chloride;Jatrochizine chloride;Nsc150445;Neprotine chloride;Yatrorhizine chloride;Jatrorrhizine hydrochloride, 98%, from Mahonia fortunei (Lindl.) Fedde
• CAS NO: 6681-15-8
• Molecular Formula: C₂₀H₂₀NO₄*Cl
• Molecular Weight: 374.842
• Mol File: 6681-15-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 208-210 °C(Solv: methanol (67-56-1))
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: JATRORRHIZINE HCL(RG)(CAS DataBase Reference)
• NIST Chemistry Reference: JATRORRHIZINE HCL(RG)(6681-15-8)
• EPA Substance Registry System: JATRORRHIZINE HCL(RG)(6681-15-8)

Safety Data

• Hazardous Substances Data: 6681-15-8(Hazardous Substances Data)

Usage

Uses

Jaztorrhizine is an alkaloid extract from the Berberidaceae family of plants displaying antioxidant activity.

InChI:InChI=1/C20H19NO4.ClH/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3;/h4-5,8-11H,6-7H2,1-3H3;1H/p+1

Upstream product

• 3213-30-7 5-(2-amino-ethyl)-2-methoxy-phenol 
• 86-51-1 2,3-dimethyoxybenzaldehyde 

Downstream Products

• 483-43-2 Jatrorrhizin 
• 6018-39-9 (+)-corypalmine 
• 6018-39-9 2,9,10-trimethoxy-berbin-3-ol 

Relevant articles and documents

A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine

Total syntheses of the antibacterial alkaloids berberine, coptisine, and jatrorrhizine have been achieved in four steps through a unified route. The key step of this strategy is an efficient intramolecular Friedel-Crafts alkoxyalkylation which, following oxidation, establishes the isoquinolinium core of these natural products. Herein, the design and development of this synthetic strategy, which has enabled the shortest and most efficient syntheses of these alkaloids reported to date, is described.