6683-94-9

Basic information

• Product Name: 1-Phenyl-2-heptanone
• Synonyms: 1-Phenyl-2-heptanone
• CAS NO: 6683-94-9
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 6683-94-9.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Density: 0.942
• CAS DataBase Reference: 1-Phenyl-2-heptanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-2-heptanone(6683-94-9)
• EPA Substance Registry System: 1-Phenyl-2-heptanone(6683-94-9)

Safety Data

• Hazardous Substances Data: 6683-94-9(Hazardous Substances Data)

Usage

Compound type

Ketone

Organic compound class

Phenyl alkyl ketones

Usage

Production of fragrances and flavors, pharmaceutical industry

Odor

Strong, sweet, and floral

Applications

Perfumes, colognes, flavoring agent in food products, reagent in organic synthesis

Upstream product

• 131973-46-1 benzyltetrabutyl stiborane 
• 142-61-0 Hexanoyl chloride 
• 14374-45-9 1-heptynylbenzene 
• 100-52-7 benzaldehyde 
• 110-43-0 n-pentyl methyl ketone 
• 16156-59-5 phenyl methanesulfonate 
• 1538551-54-0 1,3-dioxoisoindolin-2-yl butyrate 
• 119373-39-6 1-benzylcyclopropan-1-ol 
• 1078-71-3 heptylbenzene 
• 66-25-1 hexanal 
• 108-88-3 toluene 
• 10201-58-8 1-phenylhept-1-ene 
• 6921-34-2 benzylmagnesium chloride 
• 64214-56-8 N-methoxy-N-methylhexanoamide 

Downstream Products

• 143676-05-5 2-phenyl-oct-1-en-3-one 
• 65899-16-3 5-phenyl-6-undecanone 

Relevant articles and documents

Photoredox-Catalyzed Dehydrogenative Csp3-Csp2Cross-Coupling of Alkylarenes to Aldehydes in Flow

Executing photoredox reactions in flow offers solutions to frequently encountered issues regarding reproducibility, reaction time, and scale-up. Here, we report the transfer of a photoredox-catalyzed benzylic coupling of alkylarenes to aldehydes to a flow chemistry setting leading to improvements in terms of higher concentration, shorter residence times, better yields, ease of catalyst preparation, and enhanced substrate scope. Its applicability has been demonstrated by a multi-gram-scale reaction using high-power light-emitting diodes (LEDs), late-stage functionalization of selected active pharmaceutical ingredients (APIs), and also a photocatalyst recycling method.

Ni-Catalyzed β-Alkylation of Cyclopropanol-Derived Homoenolates

Metal homoenolates are valuable synthetic intermediates which provide access to β-functionalized ketones. In this report, we disclose a Ni-catalyzed β-alkylation reaction of cyclopropanol-derived homoenolates using redox-active N-hydroxyphthalimide (NHPI) esters as the alkylating reagents. The reaction is compatible with 1°, 2°, and 3° NHPI esters. Mechanistic studies imply radical activation of the NHPI ester and 2e β-carbon elimination occurring on the cyclopropanol.

Addressing challenges in palladium-catalyzed cross-couplings of aryl mesylates: Monoarylation of ketones and primary alkyl amines

Mor(DalPhos) for Me(sylates): Described are the first examples of ketone mono-α-arylation and primary aliphatic amine monoarylation employing aryl methanesulfonate coupling partners. A range of functionalized aryl mesylates were employed with dialkyl ketones, and also with primary and secondary amines as well as the otherwise challenging coupling partners acetone and methylamine. Ad=adamantyl. Copyright