66855-92-3

Basic information

• Product Name: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE
• Synonyms: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE
• CAS NO: 66855-92-3
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24328
• Mol File: 66855-92-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 367.728 °C at 760 mmHg
• Flash Point: 167.562 °C
• Appearance: /
• Density: 1.166 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(66855-92-3)
• EPA Substance Registry System: 3-(2-METHOXY-PHENOXY)-BENZALDEHYDE(66855-92-3)

Safety Data

• Hazardous Substances Data: 66855-92-3(Hazardous Substances Data)

Usage

General Description

3-(2-Methoxy-phenoxy)-benzaldehyde is a chemical compound with the molecular formula C14H12O3. It is a white to yellow solid with a sweet, floral odor. 3-(2-Methoxy-phenoxy)-benzaldehyde is commonly used in the fragrance and flavor industry, and it also has potential applications in pharmaceuticals and organic synthesis. Its aromatic structure and aldehyde group make it an important intermediate in the production of various organic compounds. Additionally, its methoxy and phenoxy groups contribute to its unique chemical and physical properties, making it a versatile building block for the synthesis of new and complex molecules.

InChI:InChI=1/C14H12O3/c1-16-13-7-2-3-8-14(13)17-12-6-4-5-11(9-12)10-15/h2-10H,1H3

Upstream product

• 87199-16-4 3-Formylphenylboronic acid 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 1179356-28-5 3-[3-(2-methoxyphenoxy)benzyl]-9-(pyrimidin-4-ylcarbonyl)-3,9-diazaspiro[5.5]undecane trifluoroacetate 
• 912461-49-5 tert-butyl 9-[3-(2-methoxyphenoxy)benzyl]-3,9-diazaspiro[5.5]undecane-3-carboxylate 
• 521975-55-3 tert-butyl-4-((1-(3-(2-methoxyphenoxy)benzyl)piperidin-4-yl)carbamoyl)-4-phenylpiperidine-1-carboxylate 
• 889654-14-2 4-amino-1-[3-(2-methoxyphenoxy)benzyl]piperidine-4-carboxylic acid methyl ester 

Relevant articles and documents

Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8)

Activation of CCR8 by its ligand CCL1 may play an important role in diseases such as asthma, multiple sclerosis, and cancer. The study of small molecule CCR8 antagonists will help establish the validation of these hypotheses. We report the design, synthesis, and progress toward optimization of potent small molecule CCR8 antagonists identified from a high-throughput screen. These analogues exhibit good potency in binding and chemotaxis assays, show good selectivity versus the hERG channel, and have good eADME (early absorption, distribution, metabolism, and excretion) profiles.

NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

The invention provides compounds of general formula wherein R and R1 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.