66863-43-2Relevant articles and documents
Hexacyclic piperazinedione compound and preparation, biological activity and application thereof
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Paragraph 0017; 0021-0022, (2020/12/14)
The invention discloses a hexacyclic piperazinedione compound as shown in the following formula: tetrahydro-beta-carboline [3: 4] piperazine-2, 5-diketopiperidine [4: 5] imidazole. The invention discloses a preparation method and application thereof. The compound not only has an anti-tumor proliferation effect, but also can inhibit migration and invasion of tumor cells, and also has an in-vivo anti-metastasis effect.
Carboline ruthenium complex as well as preparation method and application thereof
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Paragraph 0088-0090, (2020/10/14)
The invention provides a carboline ruthenium complex as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The series of carboline ruthenium complexes provided by the invention not only can in
He krien-β- [...] multifunctional particle with two cholinesterase inhibitors
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Paragraph 0062-0064, (2017/02/09)
The invention relates to the field of medicinal chemistry, and particularly relates to tacrine-beta-carboline conjoined compounds (I, II and III). The pharmacodynamic test proves that the compound disclosed by the invention can be used as a multifunction cholinesterase inhibitor, and can be clinically applied to treatment of an alzheimer disease.