66896-49-9

Basic information

• Product Name: N-methylcumylamine
• Synonyms: N-methylcumylamine
• CAS NO: 66896-49-9
• Molecular Weight: 149.236
• Mol File: 66896-49-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-methylcumylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-methylcumylamine(66896-49-9)
• EPA Substance Registry System: N-methylcumylamine(66896-49-9)

Safety Data

• Hazardous Substances Data: 66896-49-9(Hazardous Substances Data)

Upstream product

• 4747-74-4 α,α-dimethylbenzyl isocyanate 
• 826-55-1 2-methyl-2-phenylpropionic acid 
• 86972-27-2 methylene-(1-methyl-1-phenyl-ethyl)-amine 
• 934-53-2 cumenyl chloride 
• 6407-34-7 methyl-1 ethylideneamine 
• 591-51-5 phenyllithium 
• 25343-67-3 (1-isothiocyanato-1-methyl-ethyl)-benzene 

Downstream Products

• 875-30-9 1,3-dimethylindole 
• 98-83-9 isopropenylbenzene 
• 102660-50-4 N-Methyl-N-<2-phenyl-propyl-(2)>-N'-naphthyl-(1)-harnstoff 

Relevant articles and documents

Palladium(II)-Catalyzed C(sp2)-H Carbonylation of Sterically Hindered Amines with Carbon Monoxide

A palladium-catalyzed, amine-directed C(sp2)-H carbonylation of α,α-disubstituted benzylamine under 1 atm of CO for the facile synthesis of sterically hindered benzolactam has been developed. The key to success is the use of 2,2,6,6-tetramethyl-1-piperidinyloxy as the crucial sole oxidant. The synthetic utility of this transformation has been demonstrated by the first concise synthesis of the natural product spiropachysin-20-one.

RENIN INHIBITORS

The present invention relates to novel renin inhibitors of the general Formula (I), and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds. These novel renin inhibitors are used in treating cardiovascular events and renal insufficiency.