668985-72-6Relevant articles and documents
Total Synthesis and Examination of Three Key Analogues of Ramoplanin: A Lipoglycodepsipeptide with Potent Antibiotic Activity
Rew, Yosup,Shin, Dongwoo,Hwang, Inkyu,Boger, Dale L.
, p. 1041 - 1043 (2007/10/03)
The total synthesis and evaluation of three key ramoplanin aglycon analogues are detailed. The first (5a) represents replacement of the labile depsipeptide ester with a stable amide (HAsn2 → Dap2) with removal of the HAsn pendant car