67121-76-0

Basic information

• Product Name: FLUPERLAPINE
• Synonyms: FLUPERLAPINE;3-Fluoro-6-(4-methyl-1-piperazinyl)-11H-dibenz[b,e]azepine;NB-106-689
• CAS NO: 67121-76-0
• Molecular Formula: C19H20FN3
• Molecular Weight: 309.38
• Mol File: 67121-76-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 438.7 °C at 760 mmHg
• Flash Point: 219.1 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 6.74E-08mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: FLUPERLAPINE(CAS DataBase Reference)
• NIST Chemistry Reference: FLUPERLAPINE(67121-76-0)
• EPA Substance Registry System: FLUPERLAPINE(67121-76-0)

Safety Data

• Hazardous Substances Data: 67121-76-0(Hazardous Substances Data)

Usage

Uses

Fluperlapine is an agonist of the serotonin 5-HT6/5-HT7 receptors.

Metabolic pathway

Seven metabolites of fluperlapine are detected by culturing with incubation of human hepatocytes. The major metabolite is the N-oxide and the formation of sulfates remains high although decreases with time in the culture. Two glucuronides found in vivo are not detected in any of the cultures.

InChI:InChI=1/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3

Relevant articles and documents

PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES

Use of compounds of formula (I): wherein X is S, O, S=O, SO2, NRa, or CRbRc;R1,R2 are halogen, OH, SH, NH2, CN, NO2, alkyl, alkoxy, alkylamino, dialkylamino, alkylthio